Acetoanaerobium sticklandii

(aka Clostridium sticklandii)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Acetoanaerobium sticklandii, (aka Clostridium sticklandii), is a Gram-positive, spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 6 gut microbiome compilation studies or metastudies. The DNA G+C content is 31%. Acetoanaerobium sticklandii is probably a rare gut coloniser. (Stadtman1957; Rainey2011fBergey)



  • This organism has been recovered from human faeces, and black mud. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal. Robust growth can have positive consequences for gut health.
    • GENERAL CHARACTERISTICS (Stadtman1957); (Rainey2011fBergey);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows weakly at 25℃; grows weakly at 45℃; Grows optimally at 30-37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • maltose;
  • ⥅
  • Substrates assimilated or utilised:
  • arginine; glycine; isoleucine; leucine; lysine; methionine; ornithine; phenylalanine; proline; serine; threonine; tryptophan; tyrosine; valine; pyruvate;
    • SPECIAL FEATURES (Stadtman1957); (Rainey2011fBergey);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate (minor); butyrate; isobutyrate (minor); isovalerate; Hâ‚‚S; ammonia;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Acetoanaerobium Alt. name:  Clostridium sticklandii Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:   Positive
    Source:  human faeces, and black mud
    DNA G+C(%):  31
    Opt. T:  30-37℃
    Lower T(℃):  25(w)
    High T(℃):  45(w)
    		Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Galactose:  w Glucose:  w Lactose:  neg Maltose:  w(+) Sucrose:  neg Glycerol:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arg:  + Glu:  w Gly:  + Ile:  + Leu:  + Lys:  + Met:  + Orn:  + Phe:  + Pro:  + Ser:  + Thr:  + Trp:  + Tyr:  + Val:  + Lactate:  neg Pyruvate:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  minor(+) Butyrate:  + Isobutyrate:  minor(+) Isovalerate:  + H2S:  + Ammonia:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR ACETOANAEROBIUM STICKLANDII
  • Parker2016 - Nomenclature Abstract for Acetoanaerobium sticklandii (Stadtman and McClung 1957) Galperin et al. 2016.
  • Sangavai2020 - Growth-associated catabolic potential of Acetoanaerobium sticklandii DSM 519 on gelatin and amino acids.
  • Sangavai2020a - Functional prediction, characterization, and categorization of operome from Acetoanaerobium sticklandii DSM 519.
  • Stadtman1957 - Clostridium sticklandii nov. spec.
  • Rainey2011fBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Clostridiaceae, Genus I. Clostridium - Cluster XI
  • Paster1993 - Phylogeny of the ammonia-producing ruminal bacteria Peptostreptococcus anaerobius, Clostridium sticklandii, and Clostridium aminophilum sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ACETOANAEROBIUM STICKLANDII
  • Benno1986 - Comparison of the fecal microflora in rural Japanese and urban Canadians.
  • Benno1986 - Comparison of the fecal microflora in rural Japanese and urban Canadians.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Qin2012 - Metagenome-wide association study of gut microbiota in type 2 diabetes
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
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    • Added: April 08, 2021