Actinomyces dentalis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Actinomyces dentalis is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, filamentous bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 62%. Actinomyces dentalis is unlikely to be a gut coloniser. (Hall2005)



  • This organism has been recovered from clinical sources (dental abscess). The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Can cause opportunistic infections, particularly in immunocompromised people. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Produces acetic and lactic acids from glucose fermentation.
    • GENERAL CHARACTERISTICS (Hall2005);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; cellubiose; maltose; melibiose; raffinose; sucrose; trehalose;
  • Active enzymes:
  • Ala arylamidase; Arg arylamidase; α-galactosidase; α-glucosidase; β-glucosidase; Gly arylamidase; His arylamidase; Leu arylamidase; Phe arylamidase; Pro arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • β-galactosidase;
    • SPECIAL FEATURES (Hall2005);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; lactate; succinate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Actinomycetales Family:  Actinomycetaceae Genus:  Actinomyces Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Filamentous
    Health:  Unknown
    Source:  clinical sources (dental abscess)
    DNA G+C(%):  62
    		Aesculin:  + Urea:  neg Gelatin:  neg Starch:  neg Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg L-Arabinose:  neg Fructose:  + Glucose:  + Mannose:  + Ribose:  neg D-Tagatose:  neg Xylose:  neg Cellubiose:  + Lactose:  w Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  + Glycogen:  neg D-Arabitol:  neg Mannitol:  neg Sorbitol:  neg Me-α-D-Glc:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  d α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg β-Mannosidase:  neg ArgDH:  neg GluDC:  neg AlanineAA:  + AlaPheProAA:  neg ArgAA:  + GluGluAA:  neg GlyTrpAA:  neg GlyAA:  + HisAA:  + LeuAA:  + LeuGlyAA:  neg ProAA:  + PheAA:  + PyrogluAA:  neg SerAA:  neg TyrAA:  neg AlkalineP:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Lactate:  + Succinate:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR ACTINOMYCES DENTALIS
  • Nouioui2018 - Genome-Based Taxonomic Classification of the Phylum Actinobacteria.
  • Hall2005 - Actinomyces dentalis sp. nov., from a human dental abscess.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ACTINOMYCES DENTALIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: January 14, 2022