Adlercreutzia mucosicola

(aka Enterorhabdus mucosicola)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Adlercreutzia mucosicola, (aka Enterorhabdus mucosicola), is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 64.2%. Adlercreutzia mucosicola is probably a rare gut coloniser. (Clavel2009)



  • This organism has been recovered from ileal mucosa of mouse and has been detected in human faeces (Alkhalil2017). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Clavel2009);
    Character Response
  • Substrates hydrolysed or digested:
  • mucin;
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 0.5% bile
  • pH
  • Acidity tolerance:
  • tolerates pH 5.5; tolerates pH 9.5; Grows optimally at pH 6.9-7.1.
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 30-40℃.
  • ⥅
  • Substrates assimilated or utilised:
  • mucin;
  • Active enzymes:
  • Ala arylamidase; arginine dihydrolase; Gly arylamidase; His arylamidase; Leu arylamidase; Phe arylamidase; Pro arylamidase; Ser arylamidase; Tyr arylamidase;
    • SPECIAL FEATURES (Clavel2009);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
    • RESPONSE TO ANTIBIOTICS (Clavel2009);
    Class Active Resistant
  • Cephalosporins:
  • cefotaxime;
  • Macrolides:
  • clarithromycin; erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • tobramycin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Coriobacteriia Order:  Eggerthellales Family:  Eggerthellaceae Genus:  Adlercreutzia Alt. name:  Enterorhabdus mucosicola Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  ileal mucosa of mouse and has been detected in human faeces (Alkhalil2017)
    DNA G+C(%):  64.2
    Opt. T:  30-40℃
    Opt. pH:  6.9-7.1
    pH 4.2-5.9:  5.5(+)
    pH >8:  9.5(+)
    Bile reaction(%):  0.5(neg)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Coagulase:  neg ArgDH:  + AlanineAA:  + GlyAA:  + HisAA:  + LeuAA:  + ProAA:  + PheAA:  + SerAA:  + TyrAA:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    oxacillin:  Var(MIC50): 4.7), MIC90: Var(4.7
    cefotaxime:  S(1.25)
    tobramycin:  S(2.7)
    erythromycin:  S(0.048)
    clarithromycin:  S(<0.016)
    ciprofloxacin:  R(>32)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(0.12)
    vancomycin:  S(1.3)
    metronidazole:  S(0.034)
    colistin:  R(>256)

    References

    SPECIFIC REFERENCES FOR ADLERCREUTZIA MUCOSICOLA
  • Clavel2009 - Isolation of bacteria from the ileal mucosa of TNFdeltaARE mice and description of Enterorhabdus mucosicola gen. nov., sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ADLERCREUTZIA MUCOSICOLA
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • ...............................
    • GENERAL REFERENCES FOR ADLERCREUTZIA MUCOSICOLA
  • Alkhalil2017 - Bacterial involvements in ulcerative colitis: molecular and microbiological studies
    • Added: January 04, 2022