Alistipes dispar

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Alistipes dispar is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, coccobacillus bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 61.3%. Alistipes dispar is probably a rare gut coloniser. (Sakamoto2020)



  • This organism has been recovered from human faeces (Sakamoto2020). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Sakamoto2020);
    Character Response
  • 💧
  • Bile tolerance:
  • Resistant to 20% bile
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 4.2-5.9; tolerates pH 6.3-7.8; Grows optimally at pH 7.
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 15℃; grows at 25℃; grows at 37℃; doesn't grow at 41℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; mannose; lactose; maltose; raffinose; sucrose; trehalose;
  • Active enzymes:
  • N-Ac β-glucosaminidase; fucosidase; α-galactosidase; β-galactosidase;
    • SPECIAL FEATURES (Sakamoto2020);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate; succinate; indole (weak);
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS (Sakamoto2020);
    Class Active Resistant
  • Quinolines:
  • ciprofloxacin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Rikenellaceae Genus:  Alistipes Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccobacillus Pigment:  neg
    Health:  Unknown
    Source:  human faeces (Sakamoto2020)
    DNA G+C(%):  61.3
    Opt. T:  37℃
    Low T(℃):  15(neg)
    Lower T(℃):  25(+)
    Mid T(℃):  37(+)
    High T(℃):  41(neg)
    Opt. pH:  7
    pH 4.2-5.9:  4.2-5.9(neg)
    pH 6.0-8.0:  6.3-7.8(+)
    Bile reaction(%):  20(+)
    		Aesculin:  neg Gelatin:  w
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Glucose:  + Mannose:  + Rhamnose:  w Xylose:  neg Cellubiose:  w Lactose:  + Maltose:  + Melezitose:  w Sucrose:  + Trehalose:  + Glycerol:  w Mannitol:  w Sorbitol:  w Salicin:  vr
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Ac-β-glcamnd:  + α-Fucosidase:  + α-Galactosidase:  + β-Galactosidase:  + β-Glucosidase:  neg β-Mannosidase:  neg Chymotrypsin:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  + Succinate:  + Indole:  w Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)

    References

    SPECIFIC REFERENCES FOR ALISTIPES DISPAR
  • Sakamoto2020 - Alistipes communis sp. nov., Alistipes dispar sp. nov. and Alistipes onderdonkii subsp. vulgaris subsp. nov., isolated from human faeces, and creation of Alistipes onderdonkii subsp. onderdonkii subsp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ALISTIPES DISPAR
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: July 12, 2021