Alistipes ihumii

(aka Alistipes marseilloanorexicus)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Alistipes ihumii, (aka Alistipes marseilloanorexicus), is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 57.9%. Alistipes ihumii is a common gut coloniser. (Pfleiderer2014; Pfleiderer2018; Pfleiderer2013)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • In 92% of Europeans (unseenbio.com).
    • GENERAL CHARACTERISTICS (Pfleiderer2014); (Pfleiderer2018); (Pfleiderer2013);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • mannose; raffinose;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; N-Ac β-glucosaminidase; α-glucosidase; β-glucosidase; Glu-Glu arylamidase; Leu-Gly arylamidase; oxidase;
    • SPECIAL FEATURES (Pfleiderer2014);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • Haemolysis:
  • beta
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Pfleiderer2014);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; imipenem;
  • Quinolines:
  • ciprofloxacin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Rikenellaceae Genus:  Alistipes Alt. name:  Alistipes marseilloanorexicus Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces
    DNA G+C(%):  57.9
    Opt. T:  37℃
    Lower T(℃):  25(+)
    High T(℃):  45(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Mannose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  neg Urease:  neg G6PDH6PGDH:  neg α-Arab:  neg Ac-β-glcamnd:  + α-Fucosidase:  neg α-Galactosidase:  w β-Galactosidase:  neg α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg ArgDH:  neg GluDC:  w AlanineAA:  + ArgAA:  neg GluGluAA:  + GlyAA:  neg HisAA:  neg LeuAA:  neg LeuGlyAA:  + ProAA:  neg PheAA:  neg PyrogluAA:  neg SerAA:  neg TyrAA:  neg AlkalineP:  + Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    imipenem:  Sens
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Res
    clindamycin:  Sens

    References

    SPECIFIC REFERENCES FOR ALISTIPES IHUMII
  • Parker2020 - The Genus Alistipes: Gut Bacteria With Emerging Implications to Inflammation, Cancer, and Mental Health.
  • Pfleiderer2014 - Non-contiguous finished genome sequence and description of Alistipes ihumii sp. nov.
  • Luo2018 - Gut Microbiota in Human Systemic Lupus Erythematosus and a Mouse Model of Lupus
  • Pfleiderer2018 - Diversität Der Intestinalen Mikrobiota Am Beispiel Der Darmflora Einer Anorexia Patientin.
  • Pfleiderer2013 - Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ALISTIPES IHUMII
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
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    • Added: July 12, 2021