General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview


  • Alistipes megaguti is a Gram-negative, non-spore-forming, anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 58.6%. Alistipes megaguti is probably a rare gut coloniser. (Bellali2019)



  • This organism has been recovered from human faeces (Bellali2019). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.

  • GENERAL CHARACTERISTICS (Bellali2019);
    Character Response
  • pH
  • Acidity tolerance:
  • tolerates pH 7.5;
  • 🌡
  • Temperature tolerance:
  • grows at 37℃;
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; fructose; galactose; glucose; mannose; ribose; D-tagatose; xylose; amygdalin; aesculin; cellubiose; gentiobiose; lactose; maltose; melibiose; glycerol; mannitol; arbutin; N-Ac glucosamine; salicin;
  • Substrates assimilated or utilised:
  • L-arabinose; cellubiose; aesculin; glucose; lactose; maltose; mannitol; mannose; rhamnose; salicin; trehalose; xylose; tryptophan;
  • Active enzymes:
  • acid phosphatase; chymotrypsin; cystine arylamidase; esterase C4; esterase lipase C8; fucosidase; β-galactosidase; β-glucuronidase; lipase C14; α-mannosidase; trypsin; Val arylamidase; naphthol-ASBI-P;

  • Details


    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Rikenellaceae Genus:  Alistipes Gram stain:  neg O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (Bellali2019)
    DNA G+C(%):  58.6
    Mid T(℃):  37(+)
    pH 6.0-8.0:  7.5(+)
    Urea:  neg

    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  + Fructose:  + Fucose:  w D-Fucose:  w Galactose:  + Glucose:  + Mannose:  + D-Lyxose:  w Rhamnose:  neg Ribose:  + Sorbose:  neg D-Tagatose:  + Xylose:  + L-Xylose:  neg Cellubiose:  + Gentiobiose:  + Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  neg Turanose:  neg Amygdalin:  + Aesculin:  + Glycogen:  neg Inulin:  neg Starch:  w Adonitol:  w D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  w Erythritol:  neg Glycerol:  + Inositol:  w Mannitol:  + Sorbitol:  neg Xylitol:  neg Arbutin:  + Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  w Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  + Salicin:  +

    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  + Glucose:  + Mannose:  + Rhamnose:  + Xylose:  + Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  neg Raffinose:  neg Sucrose:  neg Trehalose:  + Aesculin:  + Glycerol:  neg Mannitol:  + Salicin:  + Sorbitol:  neg Trp:  +

    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  + α-Galactosidase:  neg β-Galactosidase:  + α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  + α-Mannosidase:  + Chymotrypsin:  + Trypsin:  + CystineAA:  + LeuAA:  neg ValAA:  + AlkalineP:  neg AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  +

    References


    SPECIFIC REFERENCES FOR ALISTIPES MEGAGUTI
  • Bellali2019 - Corynebacterium pacaense sp. nov., Alistipes megaguti sp. nov., Alistipes provencensis sp. nov., 3 new bacteria isolated from fresh human stool specimens.
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  • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ALISTIPES MEGAGUTI
  • New2022 - Collective effects of human genomic variation on microbiome function.
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