Alistipes onderdonkii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Alistipes onderdonkii is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 18 gut microbiome compilation studies or metastudies. The DNA G+C content is 58%. Alistipes onderdonkii is a common gut coloniser. (Sakamoto2020; Song2006; Kononen2010Bergey)



  • This organism has been recovered from human faeces and clinical sources (blood, abdominal abscess - CCUG). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Can cause opportunistic infections, particularly in immunocompromised people. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Sakamoto2020); (Song2006); (Kononen2010Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • gelatin;
  • 💧
  • Bile tolerance:
  • Resistant to 20% bile
  • H+
  • Acid from carbohydrates usually produced:
  • mannose; raffinose;
  • ⥅
  • Substrates assimilated or utilised:
  • glucose;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; acid phosphatase; N-Ac β-glucosaminidase; α-galactosidase; β-galactosidase; α-glucosidase; Glu-Glu arylamidase; Leu-Gly arylamidase; naphthol-ASBI-P;
  • ±
  • Strain-dependent active enzymes:
  • arginine dihydrolase; chymotrypsin;
    • SPECIAL FEATURES (Sakamoto2020); (Song2006); (Kononen2010Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • succinate; indole;
  • Haemolysis:
  • beta (weak)
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • NO3➔NO2:
  • not reduced
  • ✓
  • Pigments:
  • produced
    • RESPONSE TO ANTIBIOTICS (Sakamoto2020); (Kononen2010Bergey);
    Class Active Resistant
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • kanamycin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

  • Song, Yuli, Könönen, E., Rautio, M., Liu, C., Bryk, A., Eerola, E., & Finegold, S. M. (2006). Alistipes onderdonkii sp. nov. and Alistipes shahii sp. nov., of human origin. International Journal of Systematic and Evolutionary Microbiology, 56(Pt 8), 1985–1990.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Rikenellaceae Genus:  Alistipes Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  +
    Health:  Unknown
    Source:  human faeces and clinical sources (blood, abdominal abscess - CCUG)
    DNA G+C(%):  58
    Bile reaction(%):  20(+)
    		Aesculin:  vr Urea:  neg Gelatin:  + Arginine:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Mannose:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Glucose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg α-Arab:  vr Ac-β-glcamnd:  + α-Fucosidase:  vr(w) α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  d Chymotrypsin:  d GluDC:  neg Trypsin:  neg AlanineAA:  + CystineAA:  neg GluGluAA:  + GlyAA:  neg LeuAA:  neg LeuGlyAA:  + PyrrolidAA:  neg ValAA:  neg AlkalineP:  + AcidP:  + Esterase:  w EstLip(C8):  w Lipase:  neg Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Succinate:  + Indole:  + Pigment:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    kanamycin:  R(1000; disc)
    ciprofloxacin:  S(5; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  R(30; disc)
    colistin:  R(10; disc)

    References

    SPECIFIC REFERENCES FOR ALISTIPES ONDERDONKII
  • Parker2020 - The Genus Alistipes: Gut Bacteria With Emerging Implications to Inflammation, Cancer, and Mental Health.
  • Sakamoto2020 - Alistipes communis sp. nov., Alistipes dispar sp. nov. and Alistipes onderdonkii subsp. vulgaris subsp. nov., isolated from human faeces, and creation of Alistipes onderdonkii subsp. onderdonkii subsp. nov.
  • Song2006 - Alistipes onderdonkii sp. nov. and Alistipes shahii sp. nov., of human origin.
  • Kononen2010Bergey - Bergey's manual of systematic bacteriology. Vol. 4, The Bacteroidetes. Family Rikenellaceae, Genus II. Alistipes
  • Feng2015 - Gut microbiome development along the colorectal adenoma-carcinoma sequence
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • DeAngelis2013 - Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified
  • Finegold2010 - Pyrosequencing study of fecal microflora of autistic and control children
  • Giongo2011 - Toward defining the autoimmune microbiome for type 1 diabetes
  • Luo2018 - Gut Microbiota in Human Systemic Lupus Erythematosus and a Mouse Model of Lupus
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • Tang2018 - 16S rRNA gene sequencing reveals altered composition of gut microbiota in individuals with kidney stones
  • Wan2019 - Alterations of the Gut Microbiota in Multiple System Atrophy Patients
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ALISTIPES ONDERDONKII
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Chen2020 - Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Frank2007 - Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jeong2021 - The effect of taxonomic classification by full-length 16S rRNA sequencing with a synthetic long-read technology
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Pfleiderer2013 - Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
  • Urban2020 - Altered Fecal Microbiome Years after Traumatic Brain Injury
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zou2019 - 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
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    • Added: April 08, 2021