Alistipes senegalensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Alistipes senegalensis is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 9 gut microbiome compilation studies or metastudies. Alistipes senegalensis is a common gut coloniser. (Mishra2012)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • QUIRKS
  • In 97% of Europeans (unseenbio.com).
    • GENERAL CHARACTERISTICS (Mishra2012);
    Character Response
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 15℃; grows at 30℃; grows at 37℃; doesn't grow at 41℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • mannose;
  • Active enzymes:
  • Ala arylamidase; catalase; α-galactosidase; β-galactosidase; β-glucosidase; Leu-Gly arylamidase; Pro arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • Glu-Glu arylamidase;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Mishra2012);
    Class Active Resistant
  • Penicillins:
  • amoxicillin-clavulanic acid; imipenem; penicillin G;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • kanamycin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin;
  • colistin;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Rikenellaceae Genus:  Alistipes Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces
    Opt. T:  37℃
    Low T(℃):  15(neg)
    Lower T(℃):  30(+)
    Mid T(℃):  37(+)
    High T(℃):  41(neg)
    		Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Mannose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  neg β-Glucosidase:  + β-Glucuronidase:  vr ArgDH:  neg GluDC:  vr AlanineAA:  + GluGluAA:  d GlyAA:  neg LeuAA:  neg LeuGlyAA:  + ProAA:  + PyrrolidAA:  neg AlkalineP:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Augmentin:  Sens
    penicillin_G:  Sens
    imipenem:  Sens
    kanamycin:  Res
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Res
    metronidazole:  Res
    clindamycin:  Sens
    colistin:  Res

    References

    SPECIFIC REFERENCES FOR ALISTIPES SENEGALENSIS
  • Mishra2012 - Genome sequence and description of Alistipes senegalensis sp. nov.
  • Parker2020 - The Genus Alistipes: Gut Bacteria With Emerging Implications to Inflammation, Cancer, and Mental Health.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ALISTIPES SENEGALENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Chen2020 - Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
  • ...............................
    • Added: April 08, 2021