General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview


  • Alkalibacillus halophilus is a Gram-positive, spore-forming, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 39%. Alkalibacillus halophilus is likely to be transient and not a long-term gut coloniser. (Tian2007)



  • This organism has been recovered from hypersaline soil in China. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.

  • QUIRKS
  • Requires high salt (min 5%) and can grow in 30% salt, so unlikely gut coloniser.

  • GENERAL CHARACTERISTICS (Tian2007);
    Character Response
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 0% salt; tolerates 5% salt; tolerates 30% salt; Grows optimally with 10-20% salt.
  • pH
  • Acidity tolerance:
  • tolerates pH 6.5; tolerates pH 9.0; Grows optimally at pH 7.0-8.0.
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 55℃; Grows optimally at 30-45℃.
  • Substrates assimilated or utilised:
  • trehalose; xylitol;
  • Active enzymes:
  • catalase;

  • SPECIAL FEATURES (Tian2007);
    Character Response
  • Metabolites not produced:
  • Hâ‚‚S; indole;
  • Nitrate:
  • not reduced

  • RESPONSE TO ANTIBIOTICS (Tian2007);
    Class Active Resistant
  • Penicillins:
  • benzylpenicillin;
  • Tetracyclines:
  • doxycycline; tetracycline;
  • Quinolines:
  • ciprofloxacin; norfloxacin; ofloxacin;
  • Aminoglycosides:
  • amikacin; gentamicin; neomycin; tobramycin;

  • Details


    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Bacillales Family:  Bacillaceae Genus:  Alkalibacillus Gram stain:  + Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  hypersaline soil in China
    DNA G+C(%):  39
    Opt. T:  30-45℃
    Lower T(℃):  25(+)
    High T(℃):  55(+)
    NaCl 0.5-2%:  0(neg)
    NaCl 3-5%:  5(+)
    NaCl >6%:  30(+)
    Opt. pH:  7.0-8.0
    pH 6.0-8.0:  6.5(+)
    pH >8:  9.0(+)
    Gelatin:  w Starch:  neg Casein:  neg Tween:  20(neg) 80(neg)

    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Fructose:  neg Galactose:  neg Glucose:  neg Mannose:  neg Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Raffinose:  neg Sucrose:  neg Trehalose:  + Dulcitol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  + Acetate:  neg Citrate:  neg

    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  +

    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    H2S:  neg Indole:  neg

    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    benzyl-pen:  R(10; disc)
    amikacin:  R(30; disc)
    gentamicin:  R(10; disc)
    neomycin:  R(30; disc)
    tobramycin:  R(10; disc)
    ciprofloxacin:  R(5; disc)
    norfloxacin:  R(10; disc)
    ofloxacin:  R(5; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  R(30; disc)
    tetracycline:  R(30; disc)

    References


    SPECIFIC REFERENCES FOR ALKALIBACILLUS HALOPHILUS
  • Tian2007 - Alkalibacillus halophilus sp. nov., a new halophilic species isolated from hypersaline soil in Xin-Jiang province, China.
  • ...............................
  • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ALKALIBACILLUS HALOPHILUS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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