Alloprevotella tannerae

(aka Prevotella tannerae)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Alloprevotella tannerae, (aka Prevotella tannerae), is a Gram-negative, non-spore-forming, anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 11 gut microbiome compilation studies or metastudies. The DNA G+C content is 46.6%. Alloprevotella tannerae is probably a common, although minor, coloniser of the gut. (Downes2013; Moore1994; Shah2010Bergeys)



  • This organism has been recovered from human faeces and gingival crevices. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Downes2013); (Moore1994); (Shah2010Bergeys);
    Character Response
  • Substrates hydrolysed or digested:
  • gelatin; starch;
  • ±
  • Strain-dependent hydrolysis or digestion:
  • milk;
  • pH
  • Acidity tolerance:
  • tolerates pH 5.3;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; dextrin; glycogen; starch; lactose; maltose;
  • ±
  • Strain-dependent acid from carbs:
  • raffinose; sucrose; trehalose;
    • SPECIAL FEATURES (Downes2013); (Moore1994); (Shah2010Bergeys);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; isobutyrate; succinate; isovalerate; H₂S;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • Haemolysis:
  • present
  • ✗
  • Nitrate:
  • not reduced
  • Pigments:
  • variable
    • RESPONSE TO ANTIBIOTICS (Downes2013); (Goldstein2006); (Moore1994);
    Class Active Resistant
  • Penicillins:
  • amoxicillin-clavulanic acid; ampicillin-sulbactam; ertapenem; piperacillin-tazobactam;
  • Cephalosporins:
  • cefalexin; cefoxitin;
  • Macrolides:
  • azithromycin; erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Quinolines:
  • ciprofloxacin; levofloxacin;
  • Aminoglycosides:
  • kanamycin;
  • Heterocycles:
  • chloramphenicol; metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin;
  • colistin;

  • Walker, A. W., Sanderson, J. D., Churcher, C., Parkes, G. C., Hudspith, B. N., Rayment, N., Brostoff, J., Parkhill, J., Dougan, G., & Petrovska, L. (2011). High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease. BMC Microbiology, 11, 7.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Prevotellaceae Genus:  Alloprevotella Alt. name:  Prevotella tannerae Gram stain:  neg O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  variable
    Health:  Unknown
    Source:  human faeces and gingival crevices
    DNA G+C(%):  46.6
    pH 4.2-5.9:  5.3(+)
    		Aesculin:  neg Gelatin:  + Starch:  + Milk:  neg curdle Meat:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Xylose:  neg Cellubiose:  neg Lactose:  + Maltose:  + Melezitose:  neg Sucrose:  d Trehalose:  d Amygdalin:  neg Dextrin:  d(+) Aesculin:  neg Glycogen:  + Inulin:  neg Starch:  + Pectin:  neg Erythritol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  + Acetate:  + Isobutyrate:  + Succinate:  + Isovalerate:  + H2S:  + Indole:  neg Pigment:  variable
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Augmentin:  S(MIC50): 0.06, MIC90: 0.25, RNG: (≤0.015-1)
    amp-sulb:  S(MIC50): 0.125, MIC90: 1, RNG: (0.06–4)
    penicillin_G:  Var(MIC50): 0.5, MIC90: 8, RNG: (≤0.03-8)
    piper-taz:  S(≤0.06/≤0.06)
    ertapenem:  S(0.125/0.25)
    cefalexin:  S(MIC50): 1, MIC90: 4, RNG: (0.25-32)
    cefoxitin:  S(MIC50): 1, MIC90: 4, RNG: (0.125–4)
    kanamycin:  Res
    azithromycin:  S(MIC50): 0.06, MIC90: 1, RNG: (≤0.03-8)
    erythromycin:  S(MIC50): 0.125, MIC90: 1, RNG: (≤0.03-16)
    ciprofloxacin:  S(MIC50): 1, MIC90: 2, RNG: (≤0.5-4)
    levofloxacin:  S(MIC50): 0.5, MIC90: 1, RNG: (0.125-4)
    moxifloxacin:  Var(MIC50): 0.5, MIC90: 4, RNG: (0.25–16)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  R(MIC50): 4, MIC90: 32, RNG: (0.06-32)
    vancomycin:  Res
    chloramphenicol:  S(12)
    metronidazole:  S(MIC50): 0.25, MIC90: 1, RNG: (≤0.03-2)
    clindamycin:  S(MIC50): ≤0.03, MIC90: 0.25, RNG: (≤0.03->32)
    colistin:  Res

    References

    SPECIFIC REFERENCES FOR ALLOPREVOTELLA TANNERAE
  • Downes2013 - Description of Alloprevotella rava gen. nov., sp. nov., isolated from the human oral cavity, and reclassification of Prevotella tannerae Moore et al. 1994 as Alloprevotella tannerae gen. nov., comb. nov.
  • RajilicStojanovic2011 - Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome
  • Goldstein2006 - In vitro activity of moxifloxacin against 923 anaerobes isolated from human intra-abdominal infections.
  • Moore1994 - Descriptions of Prevotella tannerae sp. nov. and Prevotella enoeca sp. nov. from the Human Gingival Crevice and Emendation of the Description of Prevotella zoogleoformans.
  • Shah2010Bergeys - Bergey's manual of systematic bacteriology. Vol. 4, The Bacteroidetes. Family Prevotellaceae, Genus I. Prevotella
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ALLOPREVOTELLA TANNERAE
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Li2019b - Disordered intestinal microbes are associated with the activity of Systemic Lupus Erythematosus
  • MacFarlane2004 - Chemotaxonomic analysis of bacterial populations colonizing the rectal mucosa in patients with ulcerative colitis.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Salonen2014 - Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men.
  • Walker2011 - High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease.
  • Woodmansey2004 - Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: April 08, 2021