Alloscardovia omnicolens

(aka Bifidobacterium urinalis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Alloscardovia omnicolens, (aka Bifidobacterium urinalis), is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 6 gut microbiome compilation studies or metastudies. The DNA G+C content is 47-48%. Alloscardovia omnicolens is probably a common, although minor, coloniser of the gut. (Huys2007)



  • This organism has been recovered from human faeces and clinical sources (blood, urine, cervix - CCUG). The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Can cause opportunistic infections, particularly in immunocompromised people. A possible gut commensal.
    • QUIRKS
  • In 32% of Europeans (unseenbio.com). Minor coloniser.
    • GENERAL CHARACTERISTICS (Huys2007);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • 🌡
  • Temperature tolerance:
  • grows at 28℃; grows at 45℃;
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; glucose; xylose; maltose; raffinose; sucrose; salicin;
  • ±
  • Strain-dependent acid from carbs:
  • mannitol; sorbitol;
  • Active enzymes:
  • arabinosidase; Arg arylamidase; α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; Gly arylamidase; His arylamidase; Leu arylamidase; Phe arylamidase; Pro arylamidase; Ser arylamidase; Tyr arylamidase;
    • SPECIAL FEATURES (Huys2007);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Citron2012);
    Class Active Resistant
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Bifidobacteriales Family:  Bifidobacteriaceae Genus:  Alloscardovia Alt. name:  Bifidobacterium urinalis Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces and clinical sources (blood, urine, cervix - CCUG)
    DNA G+C(%):  47-48
    Lower T(℃):  28(+)
    High T(℃):  45(+)
    		Aesculin:  + Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + Glucose:  + Rhamnose:  neg Xylose:  + Maltose:  + Sucrose:  + Glycerol:  neg Mannitol:  d(neg) Sorbitol:  d(neg) Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg α-Arab:  d(+) Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg ArgDH:  neg GluDC:  neg AlanineAA:  neg ArgAA:  + GluGluAA:  neg GlyAA:  + HisAA:  + LeuAA:  + LeuGlyAA:  neg ProAA:  + PheAA:  + PyrogluAA:  neg SerAA:  + TyrAA:  + AlkalineP:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  S(MIC50): 0.5, MIC90: 1, RNG: (0.25–2.0)

    References

    SPECIFIC REFERENCES FOR ALLOSCARDOVIA OMNICOLENS
  • Nouioui2018 - Genome-Based Taxonomic Classification of the Phylum Actinobacteria.
  • Huys2007 - Alloscardovia omnicolens gen. nov., sp. nov., from human clinical samples.
  • Citron2012 - In vitro activities of CB-183,315, vancomycin, and metronidazole against 556 strains of Clostridium difficile, 445 other intestinal anaerobes, and 56 Enterobacteriaceae species.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ALLOSCARDOVIA OMNICOLENS
  • Almeida2019 - A new genomic blueprint of the human gut microbiota.
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: December 15, 2021