Anaerococcus lactolyticus

(aka Peptostreptococcus lactolyticus)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Anaerococcus lactolyticus, (aka Peptostreptococcus lactolyticus), is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 30-34%. Anaerococcus lactolyticus is probably a rare gut coloniser. (Ezaki2001; Li1992)



  • This organism has been recovered from vaginal discharges and ovarian abscesses. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Ezaki2001); (Li1992);
    Character Response
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; lactose;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; Arg arylamidase; β-galactosidase; Gly arylamidase; pyrrolidine arylamidase; urease;
    • SPECIAL FEATURES (Ezaki2001); (Li1992);
    Character Response
  • ✓
  • Metabolites produced:
  • propionate (minor); butyrate (major); lactate; succinate (minor);
  • ✗
  • Metabolites not produced:
  • caproate; indole;
    • RESPONSE TO ANTIBIOTICS (Tyrrell2012);
    Class Active Resistant
  • Penicillins:
  • ampicillin; imipenem; piperacillin-tazobactam;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • daptomycin; linezolid;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Tissierellia Order:  Tissierellales Family:  Peptoniphilaceae Genus:  Anaerococcus Alt. name:  Peptostreptococcus lactolyticus Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  vaginal discharges and ovarian abscesses
    DNA G+C(%):  30-34
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Glucose:  + Mannose:  + Ribose:  neg Lactose:  + Sucrose:  neg Trehalose:  neg Mannitol:  neg Sorbitol:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  + Coagulase:  neg α-Galactosidase:  neg β-Galactosidase:  + α-Glucosidase:  neg β-Glucosidase:  neg ArgDH:  neg AlanineAA:  + ArgAA:  + GlyAA:  + HisAA:  neg LeuAA:  neg ProAA:  neg PyrrolidAA:  + PheAA:  neg PyrogluAA:  neg AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Propionate:  minor(+) Butyrate:  Major(+) Lactate:  + Succinate:  minor(+) Caproate:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  S(MIC50): 0.03, MIC90: 0.25, RNG: (0.03–>8)
    piper-taz:  S(MIC50): 0.03, MIC90: 0.5, RNG: (0.03–16)
    imipenem:  S(MIC50): 0.03, MIC90: 0.06, RNG: (0.03–2)
    linezolid:  S(MIC50): 0.5, MIC90: 1, RNG: (0.25–2)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  S(MIC50): 0.25, MIC90: 0.5, RNG: (0.06–1)
    metronidazole:  S(MIC50): 0.25, MIC90: 1, RNG: (0.03–2)
    daptomycin:  S(MIC50): 0.125, MIC90: 0.5, RNG: (0.03–1)

    References

    SPECIFIC REFERENCES FOR ANAEROCOCCUS LACTOLYTICUS
  • Ezaki2001 - Proposal of the genera Anaerococcus gen. nov., Peptoniphilus gen. nov. and Gallicola gen. nov. for members of the genus Peptostreptococcus.
  • Tyrrell2012 - In vitro activity of TD-1792, a multivalent glycopeptide-cephalosporin antibiotic, against 377 strains of anaerobic bacteria and 34 strains of Corynebacterium species.
  • Li1992 - Three New Species of the Genus Peptostreptococcus Isolated from Humans: Peptostreptococcus vaginalis sp. nov., Peptostreptococcus lacrimalis sp. nov., and Peptostreptococcus lactolyticus sp. nov.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ANAEROCOCCUS LACTOLYTICUS
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: October 10, 2022