Anaerotruncus colihominis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Anaerotruncus colihominis is a Gram-positive, spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 22 gut microbiome compilation studies or metastudies. The DNA G+C content is 54%. Anaerotruncus colihominis is a common gut coloniser. (Lau2006; Lawson2011aBergey)



  • This organism has been recovered from human faeces and clinical sources (blood, abdominal fluid - CCUG). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. It is an opportunistic pathogen. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Lau2006); (Lawson2011aBergey);
    Character Response
  • pH
  • Acidity tolerance:
  • tolerates pH 5.5; tolerates pH 6.0-8.0; tolerates pH 11;
  • 🌡
  • Temperature tolerance:
  • grows at 36-40℃; Grows optimally at 36–40℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; mannose;
  • ⥅
  • Substrates assimilated or utilised:
  • N-acetylglucosamine; arbutin; cellubiose; dextrin; fructose; fucose; galactose; glucose; maltotriose; mannose; trehalose; D-turanose; serine; valine; L-malate; pyruvate; methyl-β-glucoside; methyl-β-galactoside; palatinose; α-ketovalerate; α-ketobutyrate; methyl pyruvate; thymidine; uridine; inosine;
    • SPECIAL FEATURES (Lau2006); (Lawson2011aBergey);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; butyrate; H₂; indole;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • NO3➔NO2:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Lau2006); (Lawson2011aBergey);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • Cephalosporins:
  • cefotaxime;
  • Aminoglycosides:
  • kanamycin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

  • Lawson, P. A., Song, Y., Liu, C., Molitoris, D. R., Vaisanen, M.-L., Collins, M. D., & Finegold, S. M. (2004). Anaerotruncus colihominis gen. nov., sp. nov., from human faeces. International Journal of Systematic and Evolutionary Microbiology, 54(Pt 2), 413–417.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Oscillospiraceae Genus:  Anaerotruncus Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces and clinical sources (blood, abdominal fluid - CCUG)
    DNA G+C(%):  54
    Opt. T:  36–40℃
    Mid T(℃):  36-40(+)
    pH 4.2-5.9:  5.5(+)
    pH 6.0-8.0:  6.0-8.0(+)
    pH >8:  11(+)
    		Aesculin:  neg Urea:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Glucose:  + Mannose:  + Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melibiose:  neg Trehalose:  neg Glycerol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Fructose:  + Fucose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Xylose:  neg Cellubiose:  + Lactose:  neg Maltose:  vr Maltotriose:  + Melezitose:  neg Melibiose:  neg Raffinose:  neg D-Turanose:  + Trehalose:  + N_Acetyl_glucosamine:  + Arbutin:  + Dextrin:  + Inositol:  neg Mannitol:  neg Salicin:  neg Starch:  neg Ser:  + Val:  + L-Malate:  + Pyruvate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  vr β-Glucuronidase:  neg α-Mannosidase:  neg Xylosidase:  neg ArgDH:  neg GluDC:  neg Trypsin:  neg AlanineAA:  neg ArgAA:  neg CystineAA:  neg GluGluAA:  neg GlyAA:  neg HisAA:  neg LeuAA:  neg LeuGlyAA:  neg ProAA:  neg PyrrolidAA:  neg PheAA:  neg PyrogluAA:  neg SerAA:  neg TyrAA:  neg ValAA:  neg AlkalineP:  neg Esterase(C4):  neg EstLip(C8):  neg Lipase(C14):  neg Phosphoamidase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Butyrate:  + H2:  + Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  S(0.094)
    cefotaxime:  S(0.047)
    kanamycin:  S(1000; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  S(0.5)
    metronidazole:  S(<0.016))
    colistin:  R(10; disc)

    References

    SPECIFIC REFERENCES FOR ANAEROTRUNCUS COLIHOMINIS
  • Lau2006 - Bacteraemia caused by Anaerotruncus colihominis and emended description of the species.
  • Lawson2011aBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Ruminococcaceae, Genus V. Anaerotruncus
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Hayden2020 - Fecal dysbiosis in infants with cystic fibrosis is associated with early linear growth failure
  • Ventura2019 - Gut microbiome of treatment-naïve MS patients of different ethnicities early in disease course
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ANAEROTRUNCUS COLIHOMINIS
  • Browne2016 - Culturing of 'unculturable' human microbiota reveals novel taxa and extensive sporulation.
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Chen2020 - Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • Qin2012 - Metagenome-wide association study of gut microbiota in type 2 diabetes
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
  • Salonen2014 - Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Urban2020 - Altered Fecal Microbiome Years after Traumatic Brain Injury
  • Walker2011 - High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease.
  • Wang2018 - A metagenome-wide association study of gut microbiota in asthma in UK adults
  • Wang2018a - Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • Zou2019 - 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
  • Zupancic2012 - Analysis of the Gut Microbiota in the Old Order Amish and Its Relation to the Metabolic Syndrome.
  • ...............................
    • GENERAL REFERENCES FOR ANAEROTRUNCUS COLIHOMINIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: April 08, 2021