Arthrobacter globiformis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Arthrobacter globiformis is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped-coccus cycle bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 62.0-65.5%. Arthrobacter globiformis is likely to be transient and not a long-term gut coloniser. (Busse2012Bergey)



  • This organism has been recovered from soil. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • Nonpathogenic and has been used in foods and bioremediation. Generally requires biotin for growth.
    • GENERAL CHARACTERISTICS (Busse2012Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • starch;
  • 🧂
  • Salt tolerance:
  • tolerates 0% salt; tolerates 5% salt;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 37℃; Grows optimally at 25-30℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose;
  • ⥅
  • Substrates assimilated or utilised:
  • L-arabinose; glucose; pyruvate;
  • Active enzymes:
  • α-glucosidase; α-mannosidase;
    • SPECIAL FEATURES (Busse2012Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; lactate; ethanol;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • amoxicillin; ampicillin; imipenem; meropenem; penicillin;
  • oxacillin;
  • Cephalosporins:
  • cephalothin;
  • cefotaxime;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline; tetracycline;
  • Quinolines:
  • ofloxacin;
  • Aminoglycosides:
  • gentamicin; streptomycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin; teicoplanin;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Micrococcales Family:  Micrococcaceae Genus:  Arthrobacter Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod-coccus cycle
    Health:  Unknown
    Source:  soil
    DNA G+C(%):  62.0-65.5
    Opt. T:  25-30℃
    Mid T(℃):  37(neg)
    NaCl 0.5-2%:  0(+)
    NaCl 3-5%:  5(+)
    		Urea:  neg Starch:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Glucose:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  + Glucose:  + Pyruvate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg α-Galactosidase:  neg α-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  + PyrrolidAA:  neg AcidP:  neg EstLip(C8):  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(1.2)
    ampicillin:  S(0.5)
    oxacillin:  Res
    penicillin:  S(0.25)
    imipenem:  S(1)
    meropenem:  S(2.3)
    cefotaxime:  R(6)
    cephalothin:  S(1)
    gentamicin:  S(0.56)
    streptomycin:  Sens
    erythromycin:  S(0.25)
    ciprofloxacin:  Var(MIC50): 4), MIC90: Var(4
    nalidixic-acid:  Var(MIC50): 18), MIC90: Var(18
    ofloxacin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  S(<0.37)
    tetracycline:  S(0.25)
    teicoplanin:  S(0.06)
    vancomycin:  S(0.25)
    rifampicin:  S(0.03)
    chloramphenicol:  Var(MIC50): 4), MIC90: Var(4
    SXT:  Res
    clindamycin:  S(1)

    References

    SPECIFIC REFERENCES FOR ARTHROBACTER GLOBIFORMIS
  • Busse2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Micrococcaceae, Genus III. Arthrobacter
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ARTHROBACTER GLOBIFORMIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
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    • Added: February 09, 2022