Bacillus timonensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bacillus timonensis is a Gram-negative, spore-forming, aerobic, motile, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 37.3%. Bacillus timonensis is probably a rare gut coloniser. (Afouda2017; Kokcha2012; Roux2004; Senghor2017; Hammes2011Bergey; Priest2011Bergey; Diouf2021)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal. Robust growth can have positive consequences for gut health.
    • GENERAL CHARACTERISTICS (Afouda2017); (Kokcha2012); (Roux2004); (Senghor2017); (Hammes2011Bergey); (Priest2011Bergey); (Diouf2021);
    Character Response
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 30-37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; lactose; melibiose; sucrose; trehalose; D-turanose;
  • Active enzymes:
  • chymotrypsin; esterase; α-glucosidase; β-glucosidase; β-glucuronidase; oxidase;
    • SPECIAL FEATURES (Kokcha2012); (Roux2004); (Hammes2011Bergey); (Priest2011Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
    • RESPONSE TO ANTIBIOTICS (Kokcha2012); (Roux2004);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; penicillin G;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Bacillales Family:  Bacillaceae Genus:  Bacillus Gram stain:  neg O2 Relation.:  aerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:   Positive
    Source:  human faeces
    DNA G+C(%):  37.3
    Opt. T:  30-37℃
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  + Lactose:  + Melibiose:  + Sucrose:  + Trehalose:  + Turanose:  + Aesculin:  w
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  neg α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  + Chymotrypsin:  + Esterase:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    penicillin_G:  Sens
    gentamicin:  Sens
    erythromycin:  Sens
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Sens
    vancomycin:  Sens
    rifampicin:  Sens
    SXT:  Res

    References

    SPECIFIC REFERENCES FOR BACILLUS TIMONENSIS
  • Afouda2017 - 'Lactobacillus timonensis' sp. nov., a new bacterial species isolated from the human gut.
  • Kokcha2012 - Non contiguous-finished genome sequence and description of Bacillus timonensis sp. nov.
  • Roux2004 - Paenibacillus massiliensis sp. nov., Paenibacillus sanguinis sp. nov. and Paenibacillus timonensis sp. nov., isolated from blood cultures.
  • Senghor2017 - Description of 'Bacillus dakarensis' sp. nov., 'Bacillus sinesaloumensis' sp. nov., 'Gracilibacillus timonensis' sp. nov., 'Halobacillus massiliensis' sp. nov., 'Lentibacillus massiliensis' sp. nov., 'Oceanobacillus senegalensis' sp. nov., 'Oceanobacillus timonensis' sp. nov., 'Virgibacillus dakarensis' sp. nov. and 'Virgibacillus marseillensis' sp. nov., nine halophilic new species isolated from human stool.
  • Hammes2011Bergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Lactobacillaceae, Genus I. Lactobacillus
  • Priest2011Bergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Paenibacillaceae, Genus I. Paenibacillus
  • Diouf2021 - Description of Peptoniphilus phoceensis sp. nov., and Lentibacillus timonensis sp. nov., Two New Bacteria Isolated from Fresh Stool of Human.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BACILLUS TIMONENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR BACILLUS TIMONENSIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021