Bacteroides intestinalis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bacteroides intestinalis is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 23 gut microbiome compilation studies or metastudies. The DNA G+C content is 44%. Bacteroides intestinalis is often a widespread coloniser of gut. (Bakir2006a; Song2010Bergeys)



  • This organism has been recovered from human faeces and clinical sources (blood - CCUG). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Is a rare opportunistic pathogen. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Bakir2006a); (Song2010Bergeys);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; alginate;
  • 💧
  • Bile tolerance:
  • Grows in the presence of bile
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; L-arabinose; glucose; mannose; rhamnose; xylose; cellubiose; lactose; maltose; raffinose; sucrose;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; arabinosidase; N-Ac β-glucosaminidase; α-galactosidase; β-galactosidase; β-glucosidase; glutamic acid decarboxylase; Leu-Gly arylamidase; xylosidase;
    • SPECIAL FEATURES (Bakir2006a); (Song2010Bergeys);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Lee2015); (Song2010Bergeys); (Goldstein2018a);
    Class Active Resistant
  • Penicillins:
  • imipenem; meropenem; piperacillin-tazobactam;
  • piperacillin;
  • Cephalosporins:
  • cefotetan; cefoxitin;
  • Tetracyclines:
  • tigecycline;
  • Heterocycles:
  • chloramphenicol; metronidazole;

  • Bakir, M. A., Kitahara, M., Sakamoto, M., Matsumoto, M., & Benno, Y. (2006b). Bacteroides intestinalis sp. nov., isolated from human faeces. International Journal of Systematic and Evolutionary Microbiology, 56(Pt 1), 151–154.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Bacteroidaceae Genus:  Bacteroides Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces and clinical sources (blood - CCUG)
    DNA G+C(%):  44
    Opt. T:  37℃
    Bile reaction(%):  +
    		Aesculin:  + Urea:  neg Gelatin:  neg Alginate:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + L-Arabinose:  + Glucose:  + Mannose:  + Rhamnose:  + Xylose:  + Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  neg Sucrose:  + Trehalose:  neg Glycerol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg α-Arab:  + Ac-β-glcamnd:  + α-Fucosidase:  vr α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  vr β-Glucosidase:  + β-Glucuronidase:  vr Xylosidase:  + ArgDH:  neg GluDC:  + AlanineAA:  + ArgAA:  neg GluGluAA:  vr GlyAA:  neg HisAA:  neg LeuAA:  neg LeuGlyAA:  + ProAA:  neg PyrrolidAA:  neg PheAA:  neg PyrogluAA:  neg SerAA:  neg ValAA:  neg AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    Acetate, Succinate

    		Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amp-sulb:  Var(MIC50): 4, MIC90: 16, RNG: (0.25–32)
    piperacillin:  R(128)
    piper-taz:  S(MIC50): 4, MIC90: 32, RNG: (1–64)
    imipenem:  S(MIC50): 0.5, MIC90: 2, RNG: (0.125–2)
    meropenem:  S(1)
    cefotetan:  R(128)
    cefoxitin:  R(64)
    moxifloxacin:  Var(MIC50): 2, MIC90: >16, RNG: (0.25–>16)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tigecycline:  S(MIC50): 0.25, MIC90: 4, RNG: (0.125–4)
    chloramphenicol:  S(4)
    metronidazole:  S(MIC50): 1, MIC90: 2, RNG: (0.25–2)
    clindamycin:  Var(MIC50): 1, MIC90: >32, RNG: (0.25–>32)

    References

    SPECIFIC REFERENCES FOR BACTEROIDES INTESTINALIS
  • Bakir2006a - Bacteroides intestinalis sp. nov., isolated from human faeces.
  • Lee2015 - Bacteroides faecis and Bacteroides intestinalis Recovered from Clinical Specimens of Human Intestinal Origin.
  • Wexler2007 - Bacteroides : the Good, the Bad, and the Nitty-Gritty.
  • Song2010Bergeys - Bacteroides. In Bergey's manual of systematic bacteriology: Vol. 4. The Bacteroidetes, Spirochaetes, Tenericutes (Mollicutes), Acidobacteria, Fibrobacteres, Fusobacteria, Dictyoglomi, Gemmatimonadetes, Lentisphaerae, Verrucomicrobia, Chlamydiae, and Planctomycetes
  • Cassir2015 - Clostridium butyricum Strains and Dysbiosis Linked to Necrotizing Enterocolitis in Preterm Neonates
  • DeAngelis2013 - Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified
  • Hoffman2014 - Escherichia coli dysbiosis correlates with gastrointestinal dysfunction in children with cystic fibrosis
  • Kim2020a - Altered Gut Microbiome Profile in Patients With Pulmonary Arterial Hypertension
  • Qin2012 - Metagenome-wide association study of gut microbiota in type 2 diabetes
  • RajilicStojanovic2011 - Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome
  • Wang2019b - Alterations in the human gut microbiome associated with Helicobacter pylori infection
  • Weir2013 - Stool microbiome and metabolome differences between colorectal cancer patients and healthy adults
  • Mathieu2018 - Ancient acquisition of "alginate utilization loci" by human gut microbiota.
  • Goldstein2018a - Comparative In Vitro Activities of Relebactam, Imipenem, the Combination of the Two, and Six Comparator Antimicrobial Agents against 432 Strains of Anaerobic Organisms, Including Imipenem-Resistant Strains.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BACTEROIDES INTESTINALIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Cassir2015 - Clostridium butyricum Strains and Dysbiosis Linked to Necrotizing Enterocolitis in Preterm Neonates
  • Chen2020 - Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jeong2021 - The effect of taxonomic classification by full-length 16S rRNA sequencing with a synthetic long-read technology
  • Karlsson2013 - Gut metagenome in European women with normal, impaired and diabetic glucose control
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Nielsen2014 - MetaHIT Consortium. Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
  • Salonen2014 - Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Urban2020 - Altered Fecal Microbiome Years after Traumatic Brain Injury
  • Wang2018 - A metagenome-wide association study of gut microbiota in asthma in UK adults
  • Wang2018a - Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • Zou2019 - 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
  • Zupancic2012 - Analysis of the Gut Microbiota in the Old Order Amish and Its Relation to the Metabolic Syndrome.
  • ...............................
    • GENERAL REFERENCES FOR BACTEROIDES INTESTINALIS
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
  • Song2010Bergeys - Bacteroides. In Bergey's manual of systematic bacteriology: Vol. 4. The Bacteroidetes, Spirochaetes, Tenericutes (Mollicutes), Acidobacteria, Fibrobacteres, Fusobacteria, Dictyoglomi, Gemmatimonadetes, Lentisphaerae, Verrucomicrobia, Chlamydiae, and Planctomycetes
    • Added: April 08, 2021