Bacteroides pectinophilus

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bacteroides pectinophilus is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 18 gut microbiome compilation studies or metastudies. The DNA G+C content is 45%. Bacteroides pectinophilus is a common gut coloniser. (Jensen1986)



  • This organism has been recovered from human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Can cause opportunistic infections, particularly in immunocompromised people. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Jensen1986);
    Character Response
  • Substrates hydrolysed or digested:
  • gelatin; pectin;
  • 💧
  • Bile tolerance:
  • Resistant to 20% bile
  • pH
  • Acidity tolerance:
  • tolerates pH 5.0-5.5; Grows optimally at pH 9-9.5.
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 20℃; doesn't grow at 45℃; Grows optimally at 35-40℃.
  • H+
  • Acid from carbohydrates usually produced:
  • pectin; gluconate;
  • ⥅
  • Substrates assimilated or utilised:
  • gluconate; pectin;
  • ±
  • Strain-dependent substrate utilisation:
  • fructose;
    • SPECIAL FEATURES (Jensen1986);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; lactate (minor); ethanolminor;
    • RESPONSE TO ANTIBIOTICS (Jensen1986);
    Class Active Resistant
  • Penicillins:
  • ampicillin; penicillin G;
  • Cephalosporins:
  • cephalothin;
  • Tetracyclines:
  • tetracycline;
  • Heterocycles:
  • chloramphenicol;
  • Miscellaneous antibiotics:
  • clindamycin;
  • NOTES

    Pectin, polygalacturonate, and Dgluconate
    are fermented. Occasionally, D-fructose is fermented

  • Jensen, N. S., & Canale-Parola, E. (n.d.). Bacteroides pectinophilus sp. nov. and Bacteroides galacturonicus sp. Appl Environ Microbiol, 1986;52(4):880-887, 880–887.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Bacteroidaceae Genus:  Bacteroides Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces
    DNA G+C(%):  45
    Opt. T:  35-40℃
    Lower T(℃):  20(neg)
    High T(℃):  45(neg)
    Opt. pH:  9-9.5
    pH 4.2-5.9:  5.0-5.5(+)
    Bile reaction(%):  20(+)
    		Aesculin:  neg Gelatin:  + Pectin:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg D-Arabinose:  neg L-Arabinose:  neg Fructose:  w Galactose:  neg Glucose:  neg Mannose:  neg Rhamnose:  neg Ribose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Sucrose:  neg Cellulose:  neg Inulin:  neg Starch:  neg Pectin:  + Xylan:  neg Glycerol:  neg Gluconate:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Fructose:  d Galactose:  neg Glucose:  neg Mannose:  neg Rhamnose:  neg Ribose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Sucrose:  neg Cellulose:  neg Gluconate:  + Glycerol:  neg Inulin:  neg Methanol:  neg Pectin:  + Starch:  neg Xylan:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    Acetate, Succinate

    		Formate:  + Acetate:  + Lactate:  minor(+) Ethanol:  minor
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  R(4)
    penicillin_G:  R(2U)
    cephalothin:  S(6)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(6)
    chloramphenicol:  S(12)
    clindamycin:  S(1.6)

    References

    SPECIFIC REFERENCES FOR BACTEROIDES PECTINOPHILUS
  • Jensen1986 - Bacteroides pectinophilus sp. nov. and Bacteroides galacturonicus sp. nov.: two pectinolytic bacteria from the human intestinal tract.
  • LeChatelier2013 - Richness of human gut microbiome correlates with metabolic markers
  • Li2012 - Molecular-phylogenetic characterization of the microbiota in ulcerated and non-ulcerated regions in the patients with Crohn's disease
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BACTEROIDES PECTINOPHILUS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • Karlsson2013 - Gut metagenome in European women with normal, impaired and diabetic glucose control
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • LeChatelier2013 - Richness of human gut microbiome correlates with metabolic markers
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • Nielsen2014 - MetaHIT Consortium. Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.
  • Qin2012 - Metagenome-wide association study of gut microbiota in type 2 diabetes
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Urban2020 - Altered Fecal Microbiome Years after Traumatic Brain Injury
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • Zupancic2012 - Analysis of the Gut Microbiota in the Old Order Amish and Its Relation to the Metabolic Syndrome.
  • ...............................
    • Added: April 08, 2021