Bacteroides timonensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bacteroides timonensis is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 5 gut microbiome compilation studies or metastudies. The DNA G+C content is 43.3%. Bacteroides timonensis is probably a rare gut coloniser. (Bilen2016a; Pfleiderer2013; Ramasamy2014; Pfleiderer2018)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Pfleiderer2013); (Ramasamy2014); (Pfleiderer2018);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 0.5-2.0% salt;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 37℃; Grows optimally at 37℃.
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; arabinosidase; arginine dihydrolase; N-Ac β-glucosaminidase; catalase; fucosidase; α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; glutamic acid decarboxylase; Glu-Glu arylamidase; Leu-Gly arylamidase; Pro arylamidase;
    • SPECIAL FEATURES (Ramasamy2014);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
  • ✓
  • Nitrate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Ramasamy2014);
    Class Active Resistant
  • Penicillins:
  • amoxicillin-clavulanic acid; imipenem;
  • amoxicillin;
  • Tetracyclines:
  • doxycycline;
  • Aminoglycosides:
  • gentamicin;
  • Heterocycles:
  • metronidazole; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;

  • Pfleiderer, A., Lagier, J.-C., Armougom, F., Robert, C., Vialettes, B., & Raoult, D. (2013). Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample. European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology, 32(11), 1471–1481.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Bacteroidaceae Genus:  Bacteroides Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces
    DNA G+C(%):  43.3
    Opt. T:  37℃
    Lower T(℃):  25(+)
    Mid T(℃):  37(+)
    NaCl 0.5-2%:  0.5-2.0(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg D-Arabinose:  neg L-Arabinose:  neg Fructose:  neg Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  neg Mannose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Turanose:  neg Amygdalin:  neg Aesculin:  neg Glycogen:  neg Inulin:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg α-Arab:  + Ac-β-glcamnd:  + α-Fucosidase:  + α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg ArgDH:  + GluDC:  + AlanineAA:  + ArgAA:  neg GluGluAA:  + GlyAA:  w HisAA:  neg LeuAA:  neg LeuGlyAA:  + ProAA:  + PheAA:  neg PyrogluAA:  neg SerAA:  w TyrAA:  neg AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    Acetate, Succinate

    		Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Res
    Augmentin:  Sens
    imipenem:  Sens
    gentamicin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Sens
    vancomycin:  Res
    metronidazole:  Sens
    SXT:  Sens

    References

    SPECIFIC REFERENCES FOR BACTEROIDES TIMONENSIS
  • Bilen2016a - Parabacteroides timonensis sp. nov., identified in human stool.
  • Pfleiderer2013 - Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.
  • Ramasamy2014 - Genome sequence and description of Bacteroides timonensis sp. nov.
  • Pfleiderer2018 - Diversität Der Intestinalen Mikrobiota Am Beispiel Der Darmflora Einer Anorexia Patientin.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BACTEROIDES TIMONENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Pfleiderer2013 - Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Urban2020 - Altered Fecal Microbiome Years after Traumatic Brain Injury
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    • Added: April 08, 2021