Bhargavaea beijingensis

(aka Bacillus beijingensis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bhargavaea beijingensis, (aka Bacillus beijingensis), is a Gram-positive, non-spore-forming, strictly aerobic, non-motile, coccobacillus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 53.1%. Bhargavaea beijingensis is probably a rare gut coloniser. (Verma2012; Qiu2009)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Verma2012); (Qiu2009);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; casein; gelatin; urea;
  • 🧂
  • Salt tolerance:
  • tolerates 0% salt; tolerates 8% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 5.5; tolerates pH 11; Grows optimally at pH 7-8.
  • 🌡
  • Temperature tolerance:
  • grows at 7℃; grows at 45℃; Grows optimally at 30℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; trehalose; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • inositol; D-alanine; glutamate; serine; acetate; 3-hydroxybutyrate; 2-ketoglutarate; L-malate; pyruvate; succinate; glutamine; alaninamide; α-ketovalerate; methyl succinate; succinamate; methyl pyruvate; adenosine; thymidine; uridine; inosine; D-malate;
  • Active enzymes:
  • Ala-Phe-Pro arylamidase; arginine dihydrolase; Asp arylamidase; catalase; esterase C4; esterase lipase C8; Leu arylamidase; oxidase; Phe arylamidase; pyrrolidine arylamidase; Tyr arylamidase; naphthol-ASBI-P;
    • SPECIAL FEATURES (Verma2012); (Qiu2009);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✗
  • Methyl red test:
  • not active
  • ✗
  • VP test:
  • not active
  • Lysozyme:
  • inhibited
  • Haemolysis:
  • beta
  • ✓
  • Nitrate:
  • reduced
  • ✓
  • Nitrite:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Verma2012);
    Class Active Resistant
  • Macrolides:
  • oleandomycin;
  • Aminoglycosides:
  • kanamycin;
  • Miscellaneous antibiotics:
  • polymyxin B;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Bacillales Family:  Planococcaceae Genus:  Bhargavaea Alt. name:  Bacillus beijingensis Gram stain:  + O2 Relation.:  strictly aerobic Spore:  No spore Motility:  Sessile Morphology:  Coccobacillus
    Health:  Unknown
    Source:  human faeces
    DNA G+C(%):  53.1
    Opt. T:  30℃
    Low T(℃):  7(+)
    High T(℃):  45(+)
    NaCl 0.5-2%:  0(+)
    NaCl >6%:  8(+)
    Opt. pH:  7-8
    pH 4.2-5.9:  5.5(+)
    pH >8:  11(+)
    		Aesculin:  + Urea:  + Gelatin:  + Starch:  neg Casein:  + Tween:  40(+) 80(neg)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Galactose:  neg Glucose:  neg Mannose:  neg Rhamnose:  neg Ribose:  neg D-Tagatose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  + Glycogen:  neg Inulin:  neg Adonitol:  neg Dulcitol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Me-α-D-Glc:  neg NAc-α-GA:  neg Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Fructose:  neg Mannose:  neg Rhamnose:  neg Ribose:  neg D-Tagatose:  neg Cellubiose:  neg Maltose:  neg Maltotriose:  neg Melezitose:  neg Melibiose:  neg Raffinose:  neg Sucrose:  neg D-Turanose:  neg Trehalose:  neg N_Acetyl_glucosamine:  neg Amygdalin:  neg D-Arabitol:  neg L-Arabitol:  vr Arbutin:  neg Dextrin:  neg Glycerol:  vr Glycogen:  neg Inositol:  + Inulin:  neg Mannitol:  neg Me-α-D-Glc:  neg Salicin:  neg Sorbitol:  neg Xylitol:  neg Ala:  neg D-Ala:  + Glu:  + Ser:  + Acetate:  + Citrate:  neg 3-Hydroxybutyrate:  + 2-Ketogluconate:  vr Lactate:  neg L-Malate:  + Propionate:  neg Pyruvate:  + Succinate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg β-Mannosidase:  neg Xylosidase:  neg ArgDH:  + Chymotrypsin:  neg Phe deaminase:  neg Trypsin:  neg AlanineAA:  neg AlaPheProAA:  + AspAA:  + CystineAA:  neg GlyAA:  neg LeuAA:  + ProAA:  neg PyrrolidAA:  + PheAA:  + TyrAA:  + ValAA:  neg AlkalineP:  neg AcidP:  neg Esterase(C4):  + EstLip(C8):  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    kanamycin:  Res
    oleandomycin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    polymyxin_B:  Res

    References

    SPECIFIC REFERENCES FOR BHARGAVAEA BEIJINGENSIS
  • Verma2012 - Reclassification of Bacillus beijingensis Qiu et al. 2009 and Bacillus ginsengi Qiu et al. 2009 as Bhargavaea beijingensis comb. nov. and Bhargavaea ginsengi comb. nov. and emended description of the genus Bhargavaea.
  • Qiu2009 - Bacillus beijingensis sp. nov. and Bacillus ginsengi sp. nov., isolated from ginseng root.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BHARGAVAEA BEIJINGENSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR BHARGAVAEA BEIJINGENSIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021