Bifidobacterium boum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bifidobacterium boum is a Gram-positive, non-spore-forming, anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 60.0%. Bifidobacterium boum is probably a rare gut coloniser. (Scardovi1979)



  • This organism has been recovered from human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Scardovi1979);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • ±
  • Strain-dependent hydrolysis or digestion:
  • milk;
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 4.2-5.9; grows weakly at pH 7.4; Grows optimally at pH 6.5-7.0.
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 45℃; Grows optimally at 39℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; glycogen; inulin; starch; maltose; melibiose; raffinose; sucrose; α-methyl glucoside;
  • ±
  • Strain-dependent acid from carbs:
  • lactose;
  • ⥅
  • Substrates assimilated or utilised:
  • melibiose;
    • SPECIAL FEATURES (Scardovi1979);
    Character Response
  • ✓
  • Metabolites produced:
  • formate (trace); acetate (major); lactate;
  • ✗
  • Metabolites not produced:
  • propionate; butyrate; indole;
  • ✓
  • VP test:
  • active
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; ampicillin; cloxacillin; imipenem; oxacillin; penicillin G; piperacillin; ticarcillin;
  • Cephalosporins:
  • cefotaxime; cefotetan; cefoxitin; cephalothin;
  • Macrolides:
  • erythromycin; pristinamycin; spiramycin; telithromycin;
  • Tetracyclines:
  • minocycline; tetracycline;
  • Quinolines:
  • ciprofloxacin; gatifloxacin;
  • nalidixic-acid;
  • Aminoglycosides:
  • gentamicin; kanamycin; neomycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • chloramphenicol;
  • Vancomycins:
  • vancomycin; teicoplanin;
  • Miscellaneous antibiotics:
  • lincomycin; pristinamycin; telithromycin;

  • Woodmansey, E. J., McMurdo, M. E. T., Macfarlane, G. T., & Macfarlane, S. (2004). Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects. Applied and Environmental Microbiology, 70(10), 6113–6122.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Bifidobacteriales Family:  Bifidobacteriaceae Genus:  Bifidobacterium Gram stain:  + O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces
    DNA G+C(%):  60.0
    Opt. T:  39℃
    Lower T(℃):  25(+)
    High T(℃):  45(+)
    Opt. pH:  6.5-7.0
    pH 4.2-5.9:  4.2-5.9(neg)
    pH 6.0-8.0:  7.4(w)
    		Aesculin:  + Gelatin:  neg Arginine:  neg Milk:  neg curdle
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  d(neg) Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  neg Turanose:  neg Amygdalin:  neg Glycogen:  + Inulin:  + Starch:  + Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  + Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Melibiose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  trace(+) Acetate:  Major(+) Propionate:  neg Butyrate:  neg Lactate:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    ampicillin:  Sens
    cloxacillin:  Sens
    oxacillin:  Sens
    penicillin_G:  Sens
    piperacillin:  Sens
    ticarcillin:  Sens
    imipenem:  Sens
    cefotaxime:  Sens
    cefotetan:  Sens
    cefoxitin:  Sens
    cephalothin:  Sens
    gentamicin:  Res
    kanamycin:  Res
    neomycin:  Res
    erythromycin:  Sens
    pristinamycin:  Sens
    spiramycin:  Sens
    telithromycin:  Sens
    ciprofloxacin:  Sens
    gatifloxacin:  Sens
    nalidixic-acid:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    minocycline:  Sens
    tetracycline:  Sens
    teicoplanin:  Sens
    vancomycin:  Sens
    rifampicin:  Sens
    chloramphenicol:  Sens
    metronidazole:  Var
    lincomycin:  Sens

    References

    SPECIFIC REFERENCES FOR BIFIDOBACTERIUM BOUM
  • Scardovi1979 - Bifidobacterium cuniculi, Bifidobacterium choerinum, Bifidobacterium boum, and Bifidobacterium pseudocatenulatum: Four New Species and Their Deoxyribonucleic Acid Homology Relationships.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BIFIDOBACTERIUM BOUM
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Woodmansey2004 - Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects.
  • ...............................
    • Added: April 08, 2021