Bifidobacterium catenulatum subsp. kashiwanohense

(aka Bifidobacterium kashiwanohense)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bifidobacterium catenulatum subsp. kashiwanohense, (aka Bifidobacterium kashiwanohense), is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 56-59%. Bifidobacterium catenulatum subsp. kashiwanohense is probably a rare gut coloniser. (Morita2011)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal. Robust growth can have positive consequences for gut health.
    • GENERAL CHARACTERISTICS (Morita2011);
    Character Response
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 7.2-8.0.
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 15℃; grows at 37℃; doesn't grow at 45℃;
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; fructose; galactose; glucose; mannose; ribose; xylose; cellubiose; lactose; maltose; melibiose; raffinose; sucrose; sorbitol; salicin;
  • Active enzymes:
  • acid phosphatase; esterase lipase C8; α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; Leu arylamidase;
    • SPECIAL FEATURES (Morita2011);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; lactate;
  • ✗
  • Metabolites not produced:
  • indole;
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; ampicillin; cloxacillin; imipenem; oxacillin; penicillin G; piperacillin; ticarcillin;
  • Cephalosporins:
  • cefotaxime; cefotetan; cefoxitin; cephalothin;
  • Macrolides:
  • erythromycin; pristinamycin; spiramycin; telithromycin;
  • Tetracyclines:
  • minocycline; tetracycline;
  • Quinolines:
  • ciprofloxacin; gatifloxacin;
  • nalidixic-acid;
  • Aminoglycosides:
  • gentamicin; kanamycin; neomycin;
  • Polypep/ketides:
  • nisin A; rifampicin;
  • Heterocycles:
  • chloramphenicol;
  • Vancomycins:
  • vancomycin; teicoplanin;
  • Miscellaneous antibiotics:
  • lincomycin; pristinamycin; telithromycin;

  • N/A

  • The ability of this species to efficiently utilize iron sequestration mechanisms, such as siderophore production and iron internalization, may confer an ecological advantage. [PMID: 25883283] The bifidobacteria have not been found to cause human diseases; instead, they are considered to be probiotic micro-organisms. [PMID: 21148680]

    B. kashiwanohense PV20-2 was functionally characterized and selected for its high siderophore activity and high iron internalization activity. [PMID: 25614572] B. kashiwanohense strain PV20-2 was isolated from the feces of an anemic Kenyan infant. [PMID: 25614572]

  • GutFeeling KnowledgeBase COMMENTS [Website]

    Bifidobacterium spp. are Gram-positive, anaerobic, branched rod-shaped bacteria and are frequently isolated from the human intestine. Bifidobacterium kashiwanohense JCM 15439 (= DSM 21854T) was isolated from the feces of a healthy Japanese infant. [PMID: 25883283]

  • Morita, H., Nakano, A., Onoda, H., Toh, H., Oshima, K., Takami, H., Murakami, M., Fukuda, S., Takizawa, T., Kuwahara, T., Ohno, H., Tanabe, S., & Hattori, M. (2011). Bifidobacterium kashiwanohense sp. nov., isolated from healthy infant faeces. International Journal of Systematic and Evolutionary Microbiology, 61(Pt 11), 2610–2615.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Bifidobacteriales Family:  Bifidobacteriaceae Genus:  Bifidobacterium Alt. name:  Bifidobacterium kashiwanohense Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:   Positive
    Source:  human faeces
    DNA G+C(%):  56-59
    Low T(℃):  15(neg)
    Mid T(℃):  37(+)
    High T(℃):  45(neg)
    Opt. pH:  7.2-8.0
    		Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  + Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  + Xylose:  + Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  neg Inulin:  neg Starch:  neg Glycerol:  neg Mannitol:  neg Sorbitol:  + Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  neg Chymotrypsin:  neg Trypsin:  neg CystineAA:  neg LeuAA:  + ValAA:  neg AlkalineP:  neg AcidP:  + Esterase(C4):  neg EstLip(C8):  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    Transition Metals

    Siderophore

    		 Acetate:  + Lactate:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    ampicillin:  Sens
    cloxacillin:  Sens
    oxacillin:  Sens
    penicillin_G:  Sens
    piperacillin:  Sens
    ticarcillin:  Sens
    imipenem:  Sens
    cefotaxime:  Sens
    cefotetan:  Sens
    cefoxitin:  Sens
    cephalothin:  Sens
    gentamicin:  Res
    kanamycin:  Res
    neomycin:  Res
    erythromycin:  Sens
    pristinamycin:  Sens
    spiramycin:  Sens
    telithromycin:  Sens
    ciprofloxacin:  Sens
    gatifloxacin:  Sens
    nalidixic-acid:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    minocycline:  Sens
    tetracycline:  Sens
    teicoplanin:  Sens
    vancomycin:  Sens
    nisin_A:  Sens
    rifampicin:  Sens
    chloramphenicol:  Sens
    metronidazole:  Var
    lincomycin:  Sens

    References

    SPECIFIC REFERENCES FOR BIFIDOBACTERIUM CATENULATUM SUBSP. KASHIWANOHENSE
  • Morita2011 - Bifidobacterium kashiwanohense sp. nov., isolated from healthy infant faeces.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BIFIDOBACTERIUM CATENULATUM SUBSP. KASHIWANOHENSE
  • King2019 - Baseline human gut microbiota profile in healthy people and standard reporting template.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
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    • Added: July 12, 2021