Bifidobacterium coryneforme

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bifidobacterium coryneforme is a Gram-positive, non-spore-forming, anaerobic, non-motile, club-shaped-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. Bifidobacterium coryneforme is probably a rare gut coloniser. (Biavati1982)



  • This organism has been recovered from human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Biavati1982);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; xylose; cellubiose; lactose; maltose; melibiose; sucrose; salicin;
  • ±
  • Strain-dependent acid from carbs:
  • aesculin; melezitose; raffinose; sorbitol;
    • SPECIAL FEATURES
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; lactate;
  • ✗
  • Metabolites not produced:
  • indole;
    • RESPONSE TO ANTIBIOTICS (Matteuzzi1983);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; ampicillin; cloxacillin; imipenem; oxacillin; penicillin G; piperacillin; ticarcillin;
  • Cephalosporins:
  • cefotaxime; cefotetan; cefoxitin; cephalothin;
  • Macrolides:
  • erythromycin; pristinamycin; spiramycin; telithromycin;
  • Tetracyclines:
  • minocycline; tetracycline;
  • Quinolines:
  • ciprofloxacin; gatifloxacin;
  • nalidixic-acid;
  • Aminoglycosides:
  • gentamicin; kanamycin; neomycin; streptomycin;
  • Polypep/ketides:
  • bacitracin; nisin A; rifampicin;
  • Heterocycles:
  • chloramphenicol; nitrofurantoin;
  • metronidazole;
  • Vancomycins:
  • vancomycin; teicoplanin;
  • Miscellaneous antibiotics:
  • lincomycin; pristinamycin; telithromycin;
  • polymyxin B;

  • Woodmansey, E. J., McMurdo, M. E. T., Macfarlane, G. T., & Macfarlane, S. (2004). Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects. Applied and Environmental Microbiology, 70(10), 6113–6122.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Bifidobacteriales Family:  Bifidobacteriaceae Genus:  Bifidobacterium Gram stain:  + O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Club rod
    Health:  Unknown
    Source:  human faeces
    		Aesculin:  + Gelatin:  neg Starch:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + Mannose:  neg Rhamnose:  neg Ribose:  neg Xylose:  + Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  d(neg) Melibiose:  + Sucrose:  + Trehalose:  neg Amygdalin:  vr Aesculin:  d(neg) Glycogen:  neg Starch:  neg Mannitol:  neg Sorbitol:  d(neg) Salicin:  d(+)
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Lactate:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    ampicillin:  Sens
    cloxacillin:  Sens
    oxacillin:  Sens
    penicillin_G:  S(MIC50): 0.1, MIC90: 0.1, RNG: (0.1)
    piperacillin:  Sens
    ticarcillin:  Sens
    imipenem:  Sens
    cefotaxime:  Sens
    cefotetan:  Sens
    cefoxitin:  Sens
    cephalothin:  Sens
    gentamicin:  Res
    kanamycin:  R(>1500)
    neomycin:  R(MIC50): 150, MIC90: 150, RNG: (150)
    streptomycin:  R(MIC50): 141, MIC90: 191, RNG: (200-300)
    erythromycin:  S(MIC50): 0.3, MIC90: 0.3, RNG: (0.3)
    pristinamycin:  Sens
    spiramycin:  Sens
    telithromycin:  Sens
    ciprofloxacin:  Sens
    gatifloxacin:  Sens
    nalidixic-acid:  R(>200)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    minocycline:  Sens
    tetracycline:  S(MIC50): 3.5, MIC90: 4.7, RNG: (3-5)
    teicoplanin:  Sens
    vancomycin:  Sens
    bacitracin:  S(MIC50): 0.6, MIC90: 0.92, RNG: (0.4-1)
    nisin_A:  Sens
    rifampicin:  Sens
    chloramphenicol:  S(MIC50): 5, MIC90: 5, RNG: (5)
    metronidazole:  Res
    nitrofurantoin:  S(MIC50): <20, MIC90: 27, RNG: (20-30)
    lincomycin:  Sens
    polymyxin_B:  R(>700)

    References

    SPECIFIC REFERENCES FOR BIFIDOBACTERIUM CORYNEFORME
  • Biavati1982 - Electrophoretic Patterns of Proteins in the Genus Bifidobacterium and Proposal of Four New Species.
  • Matteuzzi1983 - Antimicrobial susceptibility of Bifidobacterium.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BIFIDOBACTERIUM CORYNEFORME
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Woodmansey2004 - Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects.
  • ...............................
    • Added: April 08, 2021