Bifidobacterium scardovii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bifidobacterium scardovii is a Gram-positive, non-spore-forming, anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 60.1%. Bifidobacterium scardovii is probably a common, although minor, coloniser of the gut. (Hoyles2002)



  • This organism has been recovered from clinical sources (blood, urine - CCUG) and human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Can cause opportunistic infections, particularly in immunocompromised people. Is a known gut commensal.
    • QUIRKS
  • In 27% of Europeans (unseenbio.com). Minor coloniser.
    • GENERAL CHARACTERISTICS (Hoyles2002);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; fructose; galactose; glucose; mannose; ribose; xylose; amygdalin; starch; cellubiose; gentiobiose; lactose; maltose; D-lyxose; melibiose; raffinose; sucrose; trehalose; D-turanose; arbutin; gluconate; salicin;
  • ±
  • Strain-dependent acid from carbs:
  • 5-ketogluconate;
  • ⥅
  • Substrates assimilated or utilised:
  • melibiose;
  • Active enzymes:
  • arabinosidase; acid phosphatase; Arg arylamidase; esterase C4; fucosidase; α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; Gly arylamidase; His arylamidase; Leu arylamidase; α-mannosidase; β-mannosidase; Phe arylamidase; pyroGlu arylamidase; pyrrolidine arylamidase; Ser arylamidase; Tyr arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • urease;
    • SPECIAL FEATURES (Hoyles2002);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; lactate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • NO3➔NO2:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Barberis2017);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Quinolines:
  • ciprofloxacin; levofloxacin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin; linezolid;

  • Favier, C. F., Vaughan, E. E., De Vos, W. M., & Akkermans, A. D. L. (2002). Molecular monitoring of succession of bacterial communities in human neonates. Applied and Environmental Microbiology, 68(1), 219–226.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Bifidobacteriales Family:  Bifidobacteriaceae Genus:  Bifidobacterium Gram stain:  + O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  clinical sources (blood, urine - CCUG) and human faeces
    DNA G+C(%):  60.1
    		Aesculin:  + Urea:  vr Gelatin:  neg Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  + Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + D-Lyxose:  + Rhamnose:  neg Ribose:  + Sorbose:  neg D-Tagatose:  neg Xylose:  + L-Xylose:  neg Cellubiose:  + Gentiobiose:  + Lactose:  + Maltose:  + Melezitose:  vr Melibiose:  + Sucrose:  + Trehalose:  + Turanose:  + Amygdalin:  + Dextrin:  neg Glycogen:  neg Inulin:  neg Starch:  + Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  + Gluconate:  + 2-Ketogluconate:  neg 5-Ketogluconate:  d Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Melibiose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  d(neg) α-Arab:  + Ac-β-glcamnd:  vr α-Fucosidase:  + α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  vr α-Mannosidase:  + β-Mannosidase:  d(+) ArgDH:  neg GluDC:  neg AlanineAA:  vr AlaPheProAA:  vr ArgAA:  + GluGluAA:  neg GlyAA:  + HisAA:  + LeuAA:  + LeuGlyAA:  neg PyrrolidAA:  + PheAA:  + PyrogluAA:  + SerAA:  + TyrAA:  + AlkalineP:  neg AcidP:  + Esterase(C4):  + EstLip(C8):  vr Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Lactate:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  Sens
    erythromycin:  Sens
    linezolid:  Sens
    ciprofloxacin:  Sens
    levofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  Sens
    vancomycin:  Sens
    clindamycin:  Sens

    References

    SPECIFIC REFERENCES FOR BIFIDOBACTERIUM SCARDOVII
  • Barberis2017 - Antimicrobial susceptibility of clinical isolates of Actinomyces and related genera reveals an unusual clindamycin resistance among Actinomyces urogenitalis strains.
  • Hoyles2002 - Bifidobacterium scardovii sp. nov., from human sources.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BIFIDOBACTERIUM SCARDOVII
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • Added: April 08, 2021