Bifidobacterium subtile

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bifidobacterium subtile is a Gram-positive, non-spore-forming, anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 61.5%. Bifidobacterium subtile is probably a rare gut coloniser. (Biavati1982; Biavati2012Bergey)



  • This organism has been recovered from sewage and caries lesions. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • Non-proteolytic.
    • GENERAL CHARACTERISTICS (Biavati1982); (Biavati2012Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; starch;
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 34-36℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; glycogen; starch; maltose; melezitose; melibiose; raffinose; sucrose; sorbitol; gluconate;
  • ±
  • Strain-dependent acid from carbs:
  • ribose; inulin; cellubiose; trehalose; salicin;
    • SPECIAL FEATURES (Biavati2012Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; lactate;
  • ✗
  • Metabolites not produced:
  • indole;
    • RESPONSE TO ANTIBIOTICS (Biavati2012Bergey);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; ampicillin; imipenem; oxacillin; penicillin G; piperacillin; ticarcillin;
  • Cephalosporins:
  • cefotaxime; cefoxitin;
  • Macrolides:
  • erythromycin; pristinamycin;
  • Aminoglycosides:
  • framycetin;
  • Heterocycles:
  • chloramphenicol;
  • fusidic-acid;
  • Vancomycins:
  • teicoplanin;
  • Miscellaneous antibiotics:
  • lincomycin; linezolid; novobiocin; pristinamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Bifidobacteriales Family:  Bifidobacteriaceae Genus:  Bifidobacterium Gram stain:  + O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  sewage and caries lesions
    DNA G+C(%):  61.5
    Opt. T:  34-36℃
    		Aesculin:  + Starch:  d(+) Meat:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg Fructose:  + Galactose:  + Glucose:  + Mannose:  neg Rhamnose:  neg Ribose:  d Xylose:  neg Cellubiose:  d Lactose:  neg Maltose:  d(+) Melezitose:  d(+) Melibiose:  + Sucrose:  + Trehalose:  d(neg) Amygdalin:  neg Aesculin:  neg Glycogen:  d(+) Inulin:  d Starch:  d(+) Xylan:  neg Erythritol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  + Gluconate:  + Salicin:  d
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  + Acetate:  + Lactate:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    ampicillin:  Sens
    oxacillin:  Sens
    penicillin_G:  Sens
    piperacillin:  Sens
    ticarcillin:  Sens
    imipenem:  Sens
    cefotaxime:  Sens
    cefoxitin:  Sens
    framycetin:  Res
    erythromycin:  Sens
    pristinamycin:  Sens
    linezolid:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    teicoplanin:  Sens
    chloramphenicol:  Sens
    lincomycin:  Sens
    novobiocin:  Sens
    fusidic-acid:  Res

    References

    SPECIFIC REFERENCES FOR BIFIDOBACTERIUM SUBTILE
  • Biavati1982 - Electrophoretic Patterns of Proteins in the Genus Bifidobacterium and Proposal of Four New Species.
  • Biavati2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Bifidobacteriaceae, Genus I. Bifidobacterium
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BIFIDOBACTERIUM SUBTILE
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: March 18, 2022