Bifidobacterium thermacidophilum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bifidobacterium thermacidophilum is a Gram-positive, non-spore-forming, anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 55.4-58.3%. Bifidobacterium thermacidophilum is probably a rare gut coloniser. (Dong2000)



  • This organism has been recovered from human faeces, and an anaerobic digester. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Dong2000);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 0.5-2.0% salt; doesn't tolerate 2.5% salt;
  • pH
  • Acidity tolerance:
  • grows weakly at pH 4; Grows optimally at pH 7.0-7.2.
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 49.5℃; Grows optimally at 37-41℃.
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; fructose; galactose; melibiose; raffinose; sucrose; sorbitol;
  • ±
  • Strain-dependent acid from carbs:
  • gluconate;
    • SPECIAL FEATURES (Dong2000);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (major); lactate;
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; indole;

  • Moroni, O., Kheadr, E., Boutin, Y., Lacroix, C., & Fliss, I. (2006). Inactivation of adhesion and invasion of food-borne Listeria monocytogenes by bacteriocin-producing Bifidobacterium strains of human origin. Applied and Environmental Microbiology, 72(11), 6894–6901.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Bifidobacteriales Family:  Bifidobacteriaceae Genus:  Bifidobacterium Gram stain:  + O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces, and an anaerobic digester
    DNA G+C(%):  55.4-58.3
    Opt. T:  37-41℃
    Lower T(℃):  30(+)
    High T(℃):  49.5(+)
    NaCl 0.5-2%:  0.5-2.0(+)
    NaCl 3-5%:  2.5(neg)
    Opt. pH:  7.0-7.2
    pH 4.2-5.9:  4(w)
    		Gelatin:  neg Milk:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  + Fructose:  + Galactose:  + Mannose:  neg Rhamnose:  neg Ribose:  vr Sorbose:  neg Xylose:  vr Lactose:  vr Melezitose:  vr Melibiose:  + Sucrose:  + Trehalose:  neg Inulin:  neg Starch:  vr Mannitol:  neg Sorbitol:  + Gluconate:  d(w) Salicin:  vr
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  Major(+) Lactate:  + H2S:  neg Indole:  neg

    References

    SPECIFIC REFERENCES FOR BIFIDOBACTERIUM THERMACIDOPHILUM
  • Dong2000 - Bifidobacterium thermacidophilum sp. nov., isolated from an anaerobic digester.
  • Scanlan2012 - Gut dysbiosis in cystic fibrosis
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BIFIDOBACTERIUM THERMACIDOPHILUM
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Finegold1974 - Effect of diet on human fecal flora: comparison of Japanese and American diets
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • Added: April 08, 2021