Blautia hominis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Blautia hominis is a Gram-positive, spore-forming, strictly anaerobic, non-motile, oval-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 46.3%. Blautia hominis is probably a rare gut coloniser. (Shin2018)



  • This organism has been recovered from human faeces (Shin2018). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Shin2018);
    Character Response
  • 💧
  • Bile tolerance:
  • Resistant to 20% bile
  • 🌡
  • Temperature tolerance:
  • grows at 15℃; grows at 42℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • D-arabinose; L-arabinose; fructose; fucose; galactose; glucose; mannose; rhamnose; ribose; xylose; amygdalin; aesculin; starch; cellubiose; gentiobiose; lactose; maltose; D-lyxose; melezitose; melibiose; raffinose; sucrose; trehalose; D-turanose; D-arabitol; inositol; arbutin; gluconate; 5-ketogluconate; α-methyl glucoside; methyl mannoside; methyl xyloside; salicin;
  • Active enzymes:
  • alkaline phosphatase; arabinosidase; Arg arylamidase; N-Ac β-glucosaminidase; α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; β-glucuronidase; Gly arylamidase; Leu arylamidase; Leu-Gly arylamidase; Tyr arylamidase;
    • SPECIAL FEATURES (Shin2018);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Shin2018);
    Class Active Resistant
  • Penicillins:
  • ampicillin;
  • Cephalosporins:
  • cefoperazone;
  • Aminoglycosides:
  • gentamicin; neomycin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Lachnospiraceae Genus:  Blautia Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Oval-shaped
    Health:  Unknown
    Source:  human faeces (Shin2018)
    DNA G+C(%):  46.3
    Opt. T:  37℃
    Low T(℃):  15(+)
    High T(℃):  42(+)
    Bile reaction(%):  20(+)
    		Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  + L-Arabinose:  + Fructose:  + Fucose:  + D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + D-Lyxose:  + Rhamnose:  + Ribose:  + Sorbose:  neg D-Tagatose:  neg Xylose:  + L-Xylose:  neg Cellubiose:  + Gentiobiose:  + Lactose:  + Maltose:  + Melezitose:  + Melibiose:  + Sucrose:  + Trehalose:  + Turanose:  + Amygdalin:  + Aesculin:  + Glycogen:  neg Inulin:  neg Starch:  + Adonitol:  neg D-Arabitol:  + L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  + Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  + Gluconate:  + 2-Ketogluconate:  neg 5-Ketogluconate:  + Me-α-D-Glc:  + Me-α-D-Mann:  + Me-Xyloside:  + NAc-α-GA:  neg Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg α-Arab:  + Ac-β-glcamnd:  + α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  + ArgDH:  neg GluDC:  neg AlanineAA:  neg ArgAA:  + GluGluAA:  neg GlyAA:  + HisAA:  neg LeuAA:  + LeuGlyAA:  + ProAA:  neg PheAA:  neg PyrogluAA:  neg SerAA:  neg TyrAA:  + AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  S(10; disc)
    cefoperazone:  S(75; disc)
    gentamicin:  R(10; disc)
    neomycin:  R(75; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  S(30; disc)
    metronidazole:  S(25; disc)

    References

    SPECIFIC REFERENCES FOR BLAUTIA HOMINIS
  • Liu2021a - Blautia - a new functional genus with potential probiotic properties?.
  • Shin2018 - Blautia hominis sp. nov., isolated from human faeces.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BLAUTIA HOMINIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • ...............................
    • GENERAL REFERENCES FOR BLAUTIA HOMINIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: July 12, 2021