Blautia massiliensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Blautia massiliensis is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, coccobacillus bacterium. It has been detected in at least 5 gut microbiome compilation studies or metastudies. The DNA G+C content is 44.0%. Blautia massiliensis is a common gut coloniser. (Durand2017)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • QUIRKS
  • In 100% of Europeans (unseenbio.com).
    • GENERAL CHARACTERISTICS (Durand2017);
    Character Response
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • D-arabinose; L-arabinose; fucose; D-fucose; glucose; mannose; rhamnose; ribose; D-tagatose; xylose; L-xylose; amygdalin; aesculin; inulin; starch; cellubiose; gentiobiose; lactose; maltose; D-lyxose; melezitose; raffinose; sucrose; trehalose; dulcitol; erythritol; glycerol; mannitol; sorbitol; arbutin; gluconate; 5-ketogluconate; N-Ac glucosamine; salicin;
  • Active enzymes:
  • α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase;
    • SPECIAL FEATURES (Durand2017);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; imipenem; ticarcillin-clavulanic acid;
  • aztreonam;
  • Cephalosporins:
  • cefepime;
  • Tetracyclines:
  • tigecycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • amikacin; gentamicin; tobramycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • nitrofurantoin;
  • sulfamethoxazole;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Lachnospiraceae Genus:  Blautia Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccobacillus
    Health:  Unknown
    Source:  human faeces
    DNA G+C(%):  44.0
    Opt. T:  37℃
    		Urea:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  + L-Arabinose:  + Fucose:  + D-Fucose:  + Glucose:  + Mannose:  + D-Lyxose:  + Rhamnose:  + Ribose:  + D-Tagatose:  + Xylose:  + L-Xylose:  + Cellubiose:  + Gentiobiose:  + Lactose:  + Maltose:  + Melezitose:  + Sucrose:  + Trehalose:  + Amygdalin:  + Aesculin:  + Inulin:  + Starch:  + Dulcitol:  + Erythritol:  + Glycerol:  + Mannitol:  + Sorbitol:  + Arbutin:  + Gluconate:  + 5-Ketogluconate:  + NAc-α-GA:  + Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    aztreonam:  Res
    tica-clav:  Sens
    imipenem:  Sens
    cefepime:  Sens
    amikacin:  Res
    gentamicin:  Res
    tobramycin:  Res
    ciprofloxacin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tigecycline:  Sens
    rifampicin:  Sens
    nitrofurantoin:  Sens
    sulfamethoxazole:  Res

    References

    SPECIFIC REFERENCES FOR BLAUTIA MASSILIENSIS
  • Durand2017 - Blautia massiliensis sp. nov., isolated from a fresh human fecal sample and emended description of the genus Blautia.
  • Liu2021a - Blautia - a new functional genus with potential probiotic properties?.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BLAUTIA MASSILIENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR BLAUTIA MASSILIENSIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021