Bordetella hinzii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Bordetella hinzii is a Gram-negative, non-spore-forming, strictly aerobic, motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 65-67%. Bordetella hinzii is likely to be transient and not a long-term gut coloniser. (Vandamme1995; Sanden2005Bergey)



  • This organism has been recovered from human faeces, chicken sources, and clinical sources. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: human and animal pathogen). Is a known human pathogen. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Obligate aerobe; unlikely to be a gut coloniser.
    • GENERAL CHARACTERISTICS (Vandamme1995); (Sanden2005Bergey);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 42℃;
  • ⥅
  • Substrates assimilated or utilised:
  • aesculin; glycine; adipate; caprate; citrate; 2-ketogluconate; L-malate; malonate; phenylacetate; valerate; acetamide;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; acid phosphatase; Arg arylamidase; Asp arylamidase; catalase; esterase C4; Gly arylamidase; Leu arylamidase; Leu-Gly arylamidase; oxidase; Ser arylamidase; Tyr arylamidase; Val arylamidase; naphthol-ASBI-P;
    • SPECIAL FEATURES (Vandamme1995); (Sanden2005Bergey);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Fabre2015);
    Class Active Resistant
  • Penicillins:
  • doripenem; ertapenem; imipenem; piperacillin-tazobactam;
  • amoxicillin; amoxicillin-clavulanic acid; aztreonam; ticarcillin; ticarcillin-clavulanic acid;
  • Cephalosporins:
  • cefepime; cefotaxime; cefoxitin;
  • Tetracyclines:
  • tetracycline; tigecycline;
  • Aminoglycosides:
  • gentamicin;
  • tobramycin;
  • Heterocycles:
  • co-trimoxazole;
  • fosfomycin; fusidic-acid;
  • Vancomycins:
  • vancomycin; teicoplanin;
  • Miscellaneous antibiotics:
  • colistin;
  • clindamycin; daptomycin; linezolid;
  • NOTES

    Produces arginine arylamidase, aspartate arylamidase, serine arylamidase, tyrosine arylamidase and valine arylamidase, all of which appear to occur rarely in human gut microbes (Bergey's manual).

  • Walker, A. W., Sanderson, J. D., Churcher, C., Parkes, G. C., Hudspith, B. N., Rayment, N., Brostoff, J., Parkhill, J., Dougan, G., & Petrovska, L. (2011). High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease. BMC Microbiology, 11, 7.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Betaproteobacteria Order:  Burkholderiales Family:  Alcaligenaceae Genus:  Bordetella Gram stain:  neg O2 Relation.:  strictly aerobic Spore:  No spore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  human faeces, chicken sources, and clinical sources
    DNA G+C(%):  65-67
    Lower T(℃):  25(+)
    High T(℃):  42(+)
    		Aesculin:  neg Urea:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Glucose:  neg Rhamnose:  neg Cellubiose:  neg Maltose:  neg Sucrose:  neg Trehalose:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg 5-Ketogluconate:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Fructose:  neg Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  neg D-Lyxose:  neg Mannose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melibiose:  neg Sucrose:  neg D-Turanose:  neg Trehalose:  neg N_Acetyl_glucosamine:  neg Adonitol:  neg Amygdalin:  neg D-Arabitol:  neg L-Arabitol:  neg Arbutin:  neg Dulcitol:  neg Erythritol:  neg Aesculin:  + Gluconate:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Me-α-D-Glc:  neg Salicin:  neg Sorbitol:  neg Gly:  + Adipate:  + Caprate:  + Citrate:  + 2-Ketogluconate:  + 5-Ketogluconate:  neg L-Malate:  + Malonate:  + Phenylacetate:  + Valerate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg LysDC:  neg OrnDC:  neg Trypsin:  neg AlanineAA:  + ArgAA:  + AspAA:  + CystineAA:  neg GluGluAA:  neg GlyAA:  + LeuAA:  + LeuGlyAA:  + ProAA:  neg PheAA:  neg PyrogluAA:  neg SerAA:  + TyrAA:  + ValAA:  + AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  vr Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  R(32)
    Augmentin:  R(16-32)
    ampicillin:  RNG: (12-16)
    amp-sulb:  Var(MIC50): 8, MIC90: 16
    aztreonam:  R(>16)
    piperacillin:  RNG: (0.38-32)
    piper-taz:  SensRNG: (0.25-1)
    ticarcillin:  R(>32)
    tica-clav:  R(32-64)
    doripenem:  SensRNG: (0.125-0.5)
    ertapenem:  SensRNG: (0.023-3)
    imipenem:  SensRNG: (0.75-2)
    meropenem:  RNG: (0.125-8)
    cefepime:  R(6->16)
    cefotaxime:  R(>32)
    cefoxitin:  R(>256)
    ceftazidime:  RNG: (1.5-4)
    amikacin:  RNG: (2-16)
    gentamicin:  SensRNG: (0.75-4)
    tobramycin:  R(4-48)
    clarithromycin:  Var(MIC50): 4), MIC90: Var(4
    linezolid:  R(>256)
    ciprofloxacin:  RNG: (0.75->32)
    levofloxacin:  RNG: (0.25->32)
    moxifloxacin:  RNG: (0.5-4)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    minocycline:  RNG: (1->8)
    tetracycline:  S(0.38)
    tigecycline:  SensRNG: (0.38-0.5)
    teicoplanin:  R(>32)
    vancomycin:  R(>32)
    rifampicin:  RNG: (1->32)
    fosfomycin:  R(>256)
    co-trimoxazole:  S(MIC50): <0.5, MIC90: 9.5, RNG: (0.023-38)
    clindamycin:  R(>256)
    daptomycin:  R(>256)
    colistin:  SensRNG: (0.094-0.38)
    fusidic-acid:  R(>32)

    References

    SPECIFIC REFERENCES FOR BORDETELLA HINZII
  • Fabre2015 - Opportunistic Pulmonary Bordetella hinzii Infection after Avian Exposure.
  • Vandamme1995 - Bordetella hinzii sp. nov., Isolated from Poultry and Humans.
  • Sanden2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The The Alpha-, Beta-, Delta-, and Epsilonproteobacteria Part C. Family Alcaligenaceae, Genus III. Bordetella
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BORDETELLA HINZII
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Walker2011 - High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease.
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    • Added: April 08, 2021