Brevibacillus laterosporus

(aka Bacillus laterosporus)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Brevibacillus laterosporus, (aka Bacillus laterosporus), is a Gram-variable, spore-forming, facultatively anaerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 40%. Brevibacillus laterosporus is probably a rare gut coloniser. (Shida1996; Logan2011bBergey)



  • This organism has been recovered from soil, tap water, insects, food and clinical sources (eye infection). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Can cause opportunistic infections, particularly in immunocompromised people. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Shida1996); (Logan2011bBergey);
    Character Response
  • Substrates hydrolysed or digested:
  • casein; gelatin;
  • 🧂
  • Salt tolerance:
  • strain-variable at 5(d)%;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.8;
  • 🌡
  • Temperature tolerance:
  • grows at 20℃; strain-variable at 50(d); Grows optimally at 30℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; ribose; maltose; trehalose; glycerol; mannitol; N-Ac glucosamine;
  • ⥅
  • Substrates assimilated or utilised:
  • cellubiose; fructose; glucosamine; gentiobiose; glucose; glycerol; maltose; maltotriose; mannitol; ribose; trehalose; alanine; aspartate; glutamate; proline; serine; DL-glycerate; 3-hydroxybutyrate; succinate; glutamine;
  • ±
  • Strain-dependent substrate utilisation:
  • ethanolamine; tyrosine; L-malate;
  • Active enzymes:
  • catalase;
    • SPECIAL FEATURES (Logan2011bBergey);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • ONPG test:
  • not active
  • ✓
  • Nitrate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Reva1995);
    Class Active Resistant
  • Penicillins:
  • ampicillin; benzylpenicillin; carbenicillin; oxacillin;
  • Macrolides:
  • oleandomycin;
  • Tetracyclines:
  • tetracycline;
  • Heterocycles:
  • chloramphenicol;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Bacillales Family:  Paenibacillaceae Genus:  Brevibacillus Alt. name:  Bacillus laterosporus Gram stain:  vr O2 Relation.:  facultatively anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  soil, tap water, insects, food and clinical sources (eye infection)
    DNA G+C(%):  40
    Opt. T:  30℃
    Lower T(℃):  20(+)
    High T(℃):  50(d)
    NaCl 3-5%:  5(d)
    pH 6.0-8.0:  6.8(+)
    		Urea:  neg Gelatin:  + Starch:  neg Casein:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Fructose:  + Glucose:  + Mannose:  + Ribose:  + D-Tagatose:  neg Maltose:  + Trehalose:  + Turanose:  neg Glycerol:  + Mannitol:  + NAc-α-GA:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Fructose:  + Galactose:  neg Glucose:  + Rhamnose:  neg Ribose:  + Xylose:  neg Cellubiose:  + Gentiobiose:  + Lactose:  neg Maltose:  + Maltotriose:  + Melezitose:  neg Sucrose:  neg Trehalose:  + Adonitol:  neg L-Arabitol:  neg Ethanolamine:  d Gluconate:  neg Glucosamine:  + Glycerol:  + Inositol:  neg Mannitol:  + Me-α-D-Glc:  neg Sorbitol:  neg Ala:  + D-Ala:  neg 4-Aminobutyrate:  neg Asp:  + Glu:  + Pro:  + Ser:  + Trp:  neg Tyr:  d Aconitate:  neg Caprylate:  neg Citrate:  neg Fumarate:  neg DL-Glycerate:  + 3-Hydroxybutyrate:  + 2-Ketogluconate:  neg 5-Ketogluconate:  neg DL-Lactate:  neg Malate:  neg L-Malate:  d Malonate:  neg Mucate:  neg Phenylacetate:  neg Propionate:  neg Quinate:  neg Saccharate:  neg Succinate:  + L-Tartrate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  neg β-Galactosidase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  Sens
    benzyl-pen:  Sens
    carbenicil:  Sens
    oxacillin:  Sens
    oleandomycin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  Sens
    chloramphenicol:  Sens

    References

    SPECIFIC REFERENCES FOR BREVIBACILLUS LATEROSPORUS
  • Shida1996 - Proposal for Two New Genera, Brevibacillus gen. nov. and Aneurinibacillus gen. nov.
  • Logan2011bBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Paenibacillaceae, Genus IV. Brevibacillus
  • Laubach1916 - Spore-Bearing Bacteria in Water.
  • Reva1995 - Antibiotic Susceptibility as a Taxonomic Characteristic of the Genus Bacillus.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BREVIBACILLUS LATEROSPORUS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022