Brevibacillus thermoruber

(aka Bacillus thermoruber)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Brevibacillus thermoruber, (aka Bacillus thermoruber), is a Gram-positive, spore-forming, strictly aerobic, motile, rod-shaped bacterium. The DNA G+C content is 57%. Brevibacillus thermoruber is unlikely to be a gut coloniser. (Manachini1985; Shida1996; Logan2011bBergey)



  • This organism has been recovered from compost, human faeces (CCUG) and clinical specimens (blood - CCUG). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Can cause opportunistic infections, particularly in immunocompromised people. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Obligate aerobe and high salt required for optimum growth, so likely a gut non-coloniser.
    • GENERAL CHARACTERISTICS (Manachini1985); (Shida1996); (Logan2011bBergey);
    Character Response
  • Substrates hydrolysed or digested:
  • casein; gelatin; starch;
  • ±
  • Strain-dependent hydrolysis or digestion:
  • milk;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 5% salt;
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 7.0.
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 30℃; grows at 31℃; grows at 58℃; Grows optimally at 45-48℃.
  • ⥅
  • Substrates assimilated or utilised:
  • L-arabinose; fructose; galactose; glucose; glycerol; inositol; maltose; mannitol; ribose; trehalose; xylose;
    • SPECIAL FEATURES (Manachini1985); (Logan2011bBergey);
    Character Response
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • NO3➔NO2:
  • not reduced
  • ±
  • Pigments:
  • red
    • RESPONSE TO ANTIBIOTICS (Manachini1985);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • Tetracyclines:
  • tetracycline;
  • Heterocycles:
  • chloramphenicol;
  • Miscellaneous antibiotics:
  • novobiocin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Bacillales Family:  Paenibacillaceae Genus:  Brevibacillus Alt. name:  Bacillus thermoruber Gram stain:  + O2 Relation.:  strictly aerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod Pigment:  red
    Health:  Unknown
    Source:  compost, human faeces (CCUG) and clinical specimens (blood - CCUG)
    DNA G+C(%):  57
    Opt. T:  45-48℃
    Lower T(℃):  30(neg)
    Mid T(℃):  31(+)
    High T(℃):  58(+)
    NaCl 3-5%:  5(neg)
    Opt. pH:  7.0
    		Gelatin:  + Starch:  + Casein:  + Tyrosine:  neg Milk:  curdle
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  + Fructose:  + Galactose:  + Glucose:  + Ribose:  + Xylose:  + Maltose:  + Trehalose:  + Glycerol:  + Inositol:  + Mannitol:  + Acetate:  w Citrate:  neg L-Malate:  neg Pyruvate:  neg Succinate:  w
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg Pigment:  red
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  S(5)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(5)
    chloramphenicol:  S(50)
    novobiocin:  S(50)

    References

    SPECIFIC REFERENCES FOR BREVIBACILLUS THERMORUBER
  • Manachini1985 - Bacillus thermoruber sp. nov., nom. rev., a Red-Pigmented Thermophilic Bacterium.
  • Shida1996 - Proposal for Two New Genera, Brevibacillus gen. nov. and Aneurinibacillus gen. nov.
  • Logan2011bBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Paenibacillaceae, Genus IV. Brevibacillus
  • ...............................
    • GENERAL REFERENCES FOR BREVIBACILLUS THERMORUBER
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: July 12, 2021