Brevibacterium luteolum

(aka Brevibacterium lutescens)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Brevibacterium luteolum, (aka Brevibacterium lutescens), is a Gram-positive, non-spore-forming, aerobic, non-motile, diphtheroidal bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 68.8%. Brevibacterium luteolum is probably a rare gut coloniser. (Wauters2003a)



  • This organism has been recovered from human and environmental samples. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Is a rare opportunistic pathogen. It's gut microbiome symbiotic status is unknown.
    • QUIRKS
  • Produces methanethiol.
    • GENERAL CHARACTERISTICS (Wauters2003a);
    Character Response
  • Substrates hydrolysed or digested:
  • casein; gelatin;
  • 🧂
  • Salt tolerance:
  • tolerates 10% salt;
  • 🌡
  • Temperature tolerance:
  • grows at 20℃; Grows optimally at 30-37℃.
  • ⥅
  • Substrates assimilated or utilised:
  • γ-aminobutyrate; phenylacetate; ethylene glycol;
  • Active enzymes:
  • N-Ac β-glucosaminidase; catalase; esterase lipase C8; Leu arylamidase; lipase C14; phosphoamidase; pyrrolidine arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • alkaline phosphatase; acid phosphatase;
    • SPECIAL FEATURES (Wauters2003a);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
  • Pigments:
  • yellow
    • RESPONSE TO ANTIBIOTICS (Wauters2003a);
    Class Active Resistant
  • Penicillins:
  • ampicillin; penicillin;
  • Cephalosporins:
  • cefotaxime; cephalothin;
  • Macrolides:
  • erythromycin;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Micrococcales Family:  Brevibacteriaceae Genus:  Brevibacterium Alt. name:  Brevibacterium lutescens Gram stain:  + O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Diphtheroidal Pigment:  yellow
    Health:  Unknown
    Source:  human and environmental samples
    DNA G+C(%):  68.8
    Opt. T:  30-37℃
    Lower T(℃):  20(+)
    NaCl >6%:  10(+)
    		Aesculin:  neg Urea:  neg Gelatin:  + Casein:  + Tyrosine:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Gluconate:  neg Mannitol:  neg 4-Aminobutyrate:  + Phenylacetate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  neg Ac-β-glcamnd:  + α-Glucosidase:  neg ArgDH:  neg LysDC:  neg OrnDC:  neg LeuAA:  + PyrrolidAA:  + AlkalineP:  d(neg) AcidP:  d(neg) EstLip(C8):  + Lipase(C14):  + Phosphoamidase:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg Pigment:  yellow
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  Sens
    penicillin:  Sens
    cefotaxime:  Sens
    cephalothin:  Sens
    gentamicin:  Sens
    erythromycin:  Sens
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Sens

    References

    SPECIFIC REFERENCES FOR BREVIBACTERIUM LUTEOLUM
  • Wauters2003a - Brevibacterium lutescens sp. nov., from human and environmental samples.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BREVIBACTERIUM LUTEOLUM
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: January 14, 2022