Brevibacterium mcbrellneri

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Brevibacterium mcbrellneri is a Gram-positive, non-spore-forming, strictly aerobic, non-motile, rod-shaped-coccus cycle bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 63%. Brevibacterium mcbrellneri is likely to be transient and not a long-term gut coloniser.



  • This organism has been recovered from genital hair. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Obligate aerobe suggests it is unlikely to be a gut coloniser.
    • GENERAL CHARACTERISTICS
    Character Response
  • Substrates hydrolysed or digested:
  • casein; DNA; gelatin; milk;
  • ±
  • Strain-dependent hydrolysis or digestion:
  • xanthine;
  • 🧂
  • Salt tolerance:
  • tolerates 6.5% salt;
  • 🌡
  • Temperature tolerance:
  • grows weakly at 25℃; Grows optimally at 35-37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • ribose;
  • Active enzymes:
  • Arg arylamidase; catalase; Gly arylamidase; Leu-Gly arylamidase; Phe arylamidase; Pro arylamidase; Ser arylamidase;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • Haemolysis:
  • beta
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • ampicillin; penicillin;
  • Cephalosporins:
  • cephalothin;
  • Macrolides:
  • erythromycin;
  • Heterocycles:
  • trimethoprim;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Micrococcales Family:  Brevibacteriaceae Genus:  Brevibacterium Gram stain:  + O2 Relation.:  strictly aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod-coccus cycle
    Health:  Unknown
    Source:  genital hair
    DNA G+C(%):  63
    Opt. T:  35-37℃
    Lower T(℃):  25(w)
    NaCl >6%:  6.5(+)
    		Gelatin:  + Casein:  + Arginine:  neg DNA:  + Tyrosine:  neg Milk:  + Tween:  80(neg)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Mannose:  neg Ribose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg ArgDC:  neg LysDC:  neg OrnDC:  neg ArgAA:  + GlyAA:  + LeuGlyAA:  + ProAA:  + PheAA:  + SerAA:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  Sens
    oxacillin:  Var
    penicillin:  Sens
    cephalothin:  Sens
    erythromycin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  Var
    vancomycin:  Sens
    trimethoprim:  Sens

    References

    SPECIFIC REFERENCES FOR BREVIBACTERIUM MCBRELLNERI
  • McBride1993 - A new Brevibacterium sp. isolated from infected genital hair of patients with white piedra.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BREVIBACTERIUM MCBRELLNERI
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: October 10, 2022