Butyricimonas synergistica

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Butyricimonas synergistica is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 5 gut microbiome compilation studies or metastudies. The DNA G+C content is 44.8%. Butyricimonas synergistica is probably a common, although minor, coloniser of the gut. (Sakamoto2009; Sakamoto2014a)



  • This organism has been recovered from human faeces, and rat faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • In 54% of Europeans (unseenbio.com). A minor coloniser.
    • GENERAL CHARACTERISTICS (Sakamoto2009); (Sakamoto2014a);
    Character Response
  • Substrates hydrolysed or digested:
  • gelatin;
  • 🧂
  • Salt tolerance:
  • tolerates 0-1.8% salt;
  • 💧
  • Bile tolerance:
  • Resistant to 0-3.5% bile
  • pH
  • Acidity tolerance:
  • tolerates pH 6-7.5;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 38℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; mannose; lactose;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; N-Ac β-glucosaminidase; fucosidase; α-galactosidase; β-galactosidase; glutamic acid decarboxylase; Glu-Glu arylamidase; Leu-Gly arylamidase; pyroGlu arylamidase;
    • SPECIAL FEATURES (Sakamoto2009);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate; butyrate (major); isobutyrate (major); succinate; isovalerate (major); indole;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Pigments:
  • not produced

  • Li, M., Wang, B., Zhang, M., Rantalainen, M., Wang, S., Zhou, H., Zhang, Y., Shen, J., Pang, X., Zhang, M., Wei, H., Chen, Y., Lu, H., Zuo, J., Su, M., Qiu, Y., Jia, W., Xiao, C., Smith, L. M., … Zhao, L. (2008). Symbiotic gut microbes modulate human metabolic phenotypes. Proceedings of the National Academy of Sciences of the United States of America, 105(6), 2117–2122.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Odoribacteraceae Genus:  Butyricimonas Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  neg
    Health:  Unknown
    Source:  human faeces, and rat faeces
    DNA G+C(%):  44.8
    Opt. T:  37℃
    Lower T(℃):  25(+)
    Mid T(℃):  38(+)
    NaCl 0.5-2%:  0-1.8(+)
    pH 6.0-8.0:  6-7.5(+)
    Bile reaction(%):  0-3.5(+)
    		Aesculin:  neg Urea:  neg Gelatin:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg L-Arabinose:  neg Fructose:  neg Fucose:  neg D-Fucose:  neg Glucose:  + Mannose:  + D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg L-Sorbose:  neg D-Tagatose:  neg Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  + Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Turanose:  neg Amygdalin:  neg Glycogen:  neg Inulin:  neg Starch:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg 5-Ketogluconate:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg Ac-β-glcamnd:  + α-Fucosidase:  + α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg ArgDH:  neg GluDC:  + AlanineAA:  + GluGluAA:  + GlyAA:  neg LeuAA:  neg LeuGlyAA:  + PyrrolidAA:  neg PyrogluAA:  + AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  + Butyrate:  Major(+) Isobutyrate:  Major(+) Succinate:  + Isovalerate:  Major(+) Indole:  + Pigment:  neg

    References

    SPECIFIC REFERENCES FOR BUTYRICIMONAS SYNERGISTICA
  • Sakamoto2009 - Butyricimonas synergistica gen. nov., sp. nov. and Butyricimonas virosa sp. nov., butyric acid-producing bacteria in the family 'Porphyromonadaceae' isolated from rat faeces.
  • Sakamoto2014a - Butyricimonas faecihominis sp. nov. and Butyricimonas paravirosa sp. nov., isolated from human faeces, and emended description of the genus Butyricimonas.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BUTYRICIMONAS SYNERGISTICA
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • Added: April 08, 2021