Butyrivibrio proteoclasticus

(aka Clostridium proteoclasticum)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Butyrivibrio proteoclasticus, (aka Clostridium proteoclasticum), is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 28%. Butyrivibrio proteoclasticus is probably a rare gut coloniser. (Moon2008; Attwood1996)



  • This organism has been recovered from rumen. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Moon2008); (Attwood1996);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • ±
  • Strain-dependent hydrolysis or digestion:
  • milk;
  • 💧
  • Bile tolerance:
  • Sensitive
  • ⥅
  • Substrates assimilated or utilised:
  • amygdalin; arabinose; cellubiose; fructose; galactose; glucose; inulin; lactose; maltose; melibiose; rhamnose; salicin; starch; sucrose; xylan; xylose;
    • SPECIAL FEATURES (Attwood1996);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; propionate; butyrate; succinate (trace);
  • ✗
  • Metabolites not produced:
  • ammonia; indole;
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Lachnospiraceae Genus:  Butyrivibrio Alt. name:  Clostridium proteoclasticum Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  rumen
    DNA G+C(%):  28
    Bile reaction(%):  S
    		Aesculin:  + Milk:  curdle
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  + Fructose:  + Galactose:  + Glucose:  + Mannose:  w Rhamnose:  + Sorbose:  neg Xylose:  + Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  neg Adonitol:  neg Amygdalin:  + Cellulose:  neg Dextrin:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Glycogen:  w Inositol:  neg Inulin:  + Mannitol:  neg Salicin:  + Sorbitol:  neg Starch:  + Xylan:  + Lactate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  + Acetate:  + Propionate:  + Butyrate:  + Succinate:  trace(+) Ammonia:  neg Indole:  neg

    References

    SPECIFIC REFERENCES FOR BUTYRIVIBRIO PROTEOCLASTICUS
  • Moon2008 - Reclassification of Clostridium proteoclasticum as Butyrivibrio proteoclasticus comb. nov., a butyrate-producing ruminal bacterium.
  • Attwood1996 - Clostridium proteoclasticum sp. nov., a novel proteolytic bacterium from the bovine rumen.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR BUTYRIVIBRIO PROTEOCLASTICUS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Qin2012 - Metagenome-wide association study of gut microbiota in type 2 diabetes
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • Added: March 18, 2022