Campylobacter hyointestinalis subsp. hyointestinalis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Campylobacter hyointestinalis subsp. hyointestinalis is a Gram-negative, non-spore-forming, microaerophilic, motile, rod-shaped - curved bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 33-36%. Campylobacter hyointestinalis subsp. hyointestinalis is likely to be transient and not a long-term gut coloniser. (Gebhart1985; On1995; Vandamme1991; VanDamme2005Bergey)



  • This organism has been recovered from human faeces, human gut, and animal intestines. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: zoonotic pathogen). Could be a possible pathogen in humans, but unknown at this stage. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Gebhart1985); (On1995); (Vandamme1991); (VanDamme2005Bergey);
    Character Response
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 2% salt;
  • 💧
  • Bile tolerance:
  • Resistant to 1.5% bile
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 25(d)℃; grows at 31℃; grows at 42℃;
  • Active enzymes:
  • catalase; oxidase;
    • SPECIAL FEATURES (Gebhart1985); (On1995); (VanDamme2005Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • Hâ‚‚S (variable);
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • VP test:
  • not active
  • ±
  • Haemolysis:
  • alpha (strain dependent)
  • ✓
  • Nitrate:
  • reduced
  • ✗
  • Nitrite:
  • not reduced
  • ✓
  • NO3➔NO2:
  • reduced
  • Pigments:
  • yellow (usually)
    • RESPONSE TO ANTIBIOTICS (Gebhart1985); (On1995); (VanDamme2005Bergey);
    Class Active Resistant
  • Penicillins:
  • amoxicillin-clavulanic acid; ampicillin; carbenicillin; meropenem; penicillin; piperacillin-tazobactam; ticarcillin-clavulanic acid;
  • Cephalosporins:
  • ceftizoxime; cephalothin;
  • Tetracyclines:
  • minocycline;
  • Quinolines:
  • nalidixic-acid;
  • Aminoglycosides:
  • amikacin; gentamicin; streptomycin;
  • Polypep/ketides:
  • bacitracin;
  • Heterocycles:
  • chloramphenicol; metronidazole; nitrofurantoin;
  • trimethoprim;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin; polymyxin B;

  • Vandamme, P., Falsen, E., Rossau, R., Hoste, B., Segers, P., Tytgat, R., & De Ley, J. (1991). Revision of Campylobacter, Helicobacter, and Wolinella taxonomy: emendation of generic descriptions and proposal of Arcobacter gen. nov. International Journal of Systematic Bacteriology, 41(1), 88–103.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Epsilonproteobacteria Order:  Campylobacterales Family:  Campylobacteraceae Genus:  Campylobacter Gram stain:  neg O2 Relation.:  microaerophilic Spore:  No spore Motility:  Swimming Morphology:  Rod - curved Pigment:  yellow (usually)
    Health:  Unknown
    Source:  human faeces, human gut, and animal intestines
    DNA G+C(%):  33-36
    Lower T(℃):  25(d(neg))
    Mid T(℃):  31(+)
    High T(℃):  42(+)
    NaCl 0.5-2%:  2(neg)
    Bile reaction(%):  1.5(+)
    		Urea:  neg Gelatin:  neg Starch:  neg Casein:  neg Tyrosine:  neg Hippurate:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Gly:  vr
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  neg γ-Glu transf.:  neg AlkalineP:  vr Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  vr Indole:  neg Pigment:  yellow (usually)
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Augmentin:  S(0.06–0.5)
    ampicillin:  SensRNG: (0.25-0.5)
    carbenicil:  S(MIC50): 1-32), MIC90: S(1-32, S(32)
    penicillin:  SensRNG: (8-32)
    piperacillin:  RNG: (2-26)
    piper-taz:  S(0.016–4)
    tica-clav:  S(0.016)
    meropenem:  S(0.03)
    cefoxitin:  RNG: (1-16)
    ceftizoxime:  SensRNG: (0.25-1)
    cephalothin:  S(MIC50): 32), MIC90: S(32, vr)
    amikacin:  SensRNG: (2-8)
    gentamicin:  SensRNG: (1-2)
    kanamycin:  Var(MIC50): 4->128), MIC90: Var(4->128
    neomycin:  Var(MIC50): 4->128), MIC90: Var(4->128
    streptomycin:  SensRNG: (1-2)
    erythromycin:  Var(MIC50): 4->128), MIC90: Var(4->128
    nalidixic-acid:  R(MIC50): >128), MIC90: R(>128, R(32)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    minocycline:  SensRNG: (0.5-2)
    tetracycline:  Var(MIC50): 4->128), MIC90: Var(4->128
    vancomycin:  R(>128)
    bacitracin:  R(>128)
    rifampicin:  RNG: (4-32)
    chloramphenicol:  SensRNG: (2-16)
    metronidazole:  S(MIC50): 0.5-1), MIC90: S(0.5-1, Var(4)
    nitrofurantoin:  SensRNG: (1-2)
    trimethoprim:  R(64->128)
    clindamycin:  Var(MIC50): 1->128), MIC90: Var(1->128
    colistin:  R(>128)
    polymyxin_B:  R(64->128)

    References

    SPECIFIC REFERENCES FOR CAMPYLOBACTER HYOINTESTINALIS SUBSP. HYOINTESTINALIS
  • Gebhart1985 - Campylobacter hyointestinalis' sp. nov.: a new species of Campylobacter found in the intestines of pigs and other animals.
  • On1995 - Campylobacter hyointestinalis subsp. lawsonii subsp. nov., Isolated from the Porcine Stomach, and an Emended Description of Campylobacter hyointestinalis.
  • Vandamme1991 - Revision of Campylobacter, Helicobacter, and Wolinella Taxonomy: Emendation of Generic Descriptions and Proposal of Arcobacter gen. nov.
  • VanDamme2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Alpha-, Beta-, Delta-, and Epsilonproteobacteria Part C. Family Campylobacteraceae, Genus I. Campylobacter
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CAMPYLOBACTER HYOINTESTINALIS SUBSP. HYOINTESTINALIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR CAMPYLOBACTER HYOINTESTINALIS SUBSP. HYOINTESTINALIS
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
  • VanDamme2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Alpha-, Beta-, Delta-, and Epsilonproteobacteria Part C. Family Campylobacteraceae, Genus I. Campylobacter
  • VanDamme2005aBergey - Bergey's manual of systematic bacteriology. Vol. 2, The Alpha-, Beta-, Delta-, and Epsilonproteobacteria Part C. Family Campylobacteraceae, Genus II. Arcobacter
    • Added: July 12, 2021