Capnocytophaga gingivalis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Capnocytophaga gingivalis is a Gram-negative, non-spore-forming, facultatively anaerobic, gliding, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 35-41%. Capnocytophaga gingivalis is unlikely to be a gut coloniser. (Leadbetter1979; London1985; Kristiansen1984)



  • This organism has been recovered from oral flora. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Could be a possible pathogen in humans, but unknown at this stage. It's gut microbiome symbiotic status is unknown.
    • QUIRKS
  • Grows better in air by completely respiring glucose
    • GENERAL CHARACTERISTICS (Leadbetter1979); (London1985); (Kristiansen1984);
    Character Response
  • Substrates hydrolysed or digested:
  • DNA;
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; mannose; maltose; sucrose;
  • ⥅
  • Substrates assimilated or utilised:
  • glucose;
  • Active enzymes:
  • cystine arylamidase; α-glucosidase; Leu arylamidase; Val arylamidase;
    • SPECIAL FEATURES (Leadbetter1979); (London1985); (Kristiansen1984);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate (minor); lactate (minor); succinate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • ONPG test:
  • not active
  • Pigments:
  • orange
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Macrolides:
  • spiramycin;
  • Tetracyclines:
  • doxycycline;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Flavobacteriia Order:  Flavobacteriales Family:  Flavobacteriaceae Genus:  Capnocytophaga Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Gliding Morphology:  Rod Pigment:  orange
    Health:  Unknown
    Source:  oral flora
    DNA G+C(%):  35-41
    Opt. T:  37℃
    Lower T(℃):  30(+)
    		Aesculin:  neg Gelatin:  neg Agar:  neg Chitin:  neg DNA:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Fructose:  neg Galactose:  neg Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Xylose:  neg Cellubiose:  neg Maltose:  + Melezitose:  neg Sucrose:  + Trehalose:  neg Aesculin:  neg Glycogen:  neg Starch:  neg Mannitol:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Glucose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg α-Glucosidase:  + ArgDC:  neg LysDC:  neg OrnDC:  neg CystineAA:  + LeuAA:  + ValAA:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  minor(+) Lactate:  minor(+) Succinate:  + Indole:  neg Pigment:  orange
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    spiramycin:  R(64)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  S(0.5)

    References

    SPECIFIC REFERENCES FOR CAPNOCYTOPHAGA GINGIVALIS
  • Leadbetter1979 - Capnocytophaga: New genus of gram-negative gliding bacteria I. General characteristics, taxonomic considerations and significance.
  • London1985 - Emended Description of Capnocytophaga gingivalis
  • Kristiansen1984 - Rapid identification of Capnocytophaga isolated from septicemic patients.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CAPNOCYTOPHAGA GINGIVALIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: January 14, 2022