Cedecea davisae

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Cedecea davisae is a Gram-negative, non-spore-forming, facultatively anaerobic, motile, rod-shaped bacterium. It has been detected in at least 5 gut microbiome compilation studies or metastudies. The DNA G+C content is 49-50%. Cedecea davisae is probably a rare gut coloniser. (Farmer1985; Grimont1981; Farmer2005Bergey)



  • This organism has been recovered from human faeces, and clinical sources. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Farmer1985); (Grimont1981); (Farmer2005Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • 🧂
  • Salt tolerance:
  • tolerates 0% salt; tolerates 6% salt;
  • 🌡
  • Temperature tolerance:
  • grows at 5℃; doesn't grow at 40℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • D-arabinose; glucose; mannose; amygdalin; cellubiose; maltose; sucrose; trehalose; D-arabitol; mannitol; salicin;
  • ±
  • Strain-dependent acid from carbs:
  • lactose; α-methyl glucoside;
  • ⥅
  • Substrates assimilated or utilised:
  • N-acetylglucosamine; d_arabitol; cellubiose; fructose; galactose; gluconate; glucosamine; gentiobiose; glucose; glycerol; inositol; maltose; mannitol; mannose; ribose; salicin; sucrose; trehalose; D-turanose; xylose; alanine; D-alanine; glutamate; proline; citrate; fumarate; DL-glycerate; 2-ketoglutarate; DL-lactate; L-malate; pyruvate; glutamine; 4-aminobenzoate; D-glucuronate;
  • Active enzymes:
  • arginine decarboxylase; catalase; α-glucosidase; β-glucosidase; lipase; ornithine decarboxylase;
    • SPECIAL FEATURES (Farmer1985); (Grimont1981); (Farmer2005Bergey);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • VP test:
  • activity is variable
  • ✓
  • ONPG test:
  • active
  • KCN growth:
  • growth observed
  • ✓
  • NO3➔NO2:
  • reduced
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS (Grimont1981); (Kanakadandi2019); (Farmer2005Bergey);
    Class Active Resistant
  • Penicillins:
  • carbenicillin;
  • ampicillin; penicillin;
  • Cephalosporins:
  • cefuroxime; cephalothin;
  • Macrolides:
  • telithromycin;
  • Tetracyclines:
  • minocycline; tetracycline;
  • Quinolines:
  • ciprofloxacin; nalidixic-acid;
  • Aminoglycosides:
  • amikacin; gentamicin; kanamycin; streptomycin; tobramycin;
  • Heterocycles:
  • chloramphenicol; metronidazole; nitrofurantoin; sulfadiazine; trimethoprim;
  • Miscellaneous antibiotics:
  • telithromycin; vibriostatin A 0 129;
  • colistin; polymyxin B;

  • Grimont, P. A. D., Grimont, F., Farmer, J. J., & Asbury, M. A. (1981). Cedecea davisae gen. nov., sp. nov. and Cedecea lapagei sp. nov., New Enterobacteriaceae from Clinical Specimens. International Journal of Systematic Bacteriology, 31(3), 317–326.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Gammaproteobacteria Order:  Enterobacterales Family:  Enterobacteriaceae Genus:  Cedecea Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Swimming Morphology:  Rod Pigment:  neg
    Health:  Unknown
    Source:  human faeces, and clinical sources
    DNA G+C(%):  49-50
    Opt. T:  37℃
    Low T(℃):  5(+)
    Mid T(℃):  40(neg)
    NaCl 0.5-2%:  0(+)
    NaCl >6%:  6(+)
    		Aesculin:  + Urea:  neg Gelatin:  neg Starch:  neg Chitin:  neg DNA:  neg Tyrosine:  neg Tween:  40(+) 60(+) 80(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg D-Arabinose:  + L-Arabinose:  neg Glucose:  + Mannose:  + Rhamnose:  neg Cellubiose:  + Lactose:  d(neg) Maltose:  + Melibiose:  neg Sucrose:  + Trehalose:  + Amygdalin:  + Aesculin:  vr Adonitol:  neg D-Arabitol:  + L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  vr Mannitol:  + Sorbitol:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  d(neg) Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  + Sorbose:  neg D-Tagatose:  neg Xylose:  + Cellubiose:  + Gentiobiose:  + Lactose:  neg Maltose:  + Melezitose:  neg Melibiose:  neg Raffinose:  neg Sucrose:  + D-Turanose:  + Trehalose:  + N_Acetyl_glucosamine:  + Adonitol:  neg D-Arabitol:  + Dulcitol:  neg Erythritol:  neg Ethanol:  neg Gluconate:  + Glucosamine:  + Glycerol:  + Inositol:  d(+) Mannitol:  + Me-α-D-Glc:  w Methanol:  neg Propanol:  neg Salicin:  + Sorbitol:  neg Xylitol:  neg Ala:  + D-Ala:  + β-Ala:  neg 4-Aminobutyrate:  vr Arg:  neg Asp:  w Betaine:  neg L-Citrulline:  neg Cys:  neg Glu:  + Gly:  neg Histamine:  neg His:  neg Ile:  neg DL-Kynurenine:  neg Leu:  neg Lys:  neg Met:  neg Norleucine:  neg Orn:  neg Phe:  neg Pro:  + Sarcosine:  neg Ser:  w Thr:  neg Trigonelline:  neg Tryptamine:  neg Trp:  neg Tyr:  neg Val:  neg Acetate:  w Aconitate:  neg Adipate:  neg Azelate:  neg Benzoate:  neg Butyrate:  neg Caprate:  neg Caproate:  neg Caprylate:  neg Citrate:  + Fumarate:  + Glutarate:  neg DL-Glycerate:  + Glycolate:  neg Heptanoate:  neg 3-Hydroxybenzoate:  neg 4-Hydroxybenzoate:  neg Isobutyrate:  neg Isovalerate:  neg DL-Lactate:  + L-Malate:  + Maleate:  neg Malonate:  w L-Mandelate:  neg Mucate:  neg Nonanoate:  neg Pimelate:  neg Propionate:  neg Pyruvate:  + Quinate:  neg Suberate:  neg Succinate:  w D-Tartrate:  neg L-Tartrate:  neg Valerate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg Ac-β-glcamnd:  vr α-Galactosidase:  neg β-Galactosidase:  vr α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg ArgDC:  + LysDC:  neg OrnDC:  + Phe deaminase:  neg DNAse:  neg Lipase:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  Res
    carbenicil:  Sens
    penicillin:  Res
    cefuroxime:  Res
    cephalothin:  Res
    amikacin:  Sens
    gentamicin:  Sens
    kanamycin:  Sens
    streptomycin:  Sens
    tobramycin:  Sens
    telithromycin:  Sens
    ciprofloxacin:  S(clinic,500)
    nalidixic-acid:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    minocycline:  Sens
    tetracycline:  Sens
    chloramphenicol:  Sens
    metronidazole:  S(clinic,500)
    nitrofurantoin:  Sens
    sulfadiazine:  Sens
    trimethoprim:  Sens
    colistin:  Res
    polymyxin_B:  Res
    vibriostat_129:  Sens

    References

    SPECIFIC REFERENCES FOR CEDECEA DAVISAE
  • Farmer1985 - Biochemical identification of new species and biogroups of Enterobacteriaceae isolated from clinical specimens.
  • Grimont1981 - Cedecea davisae gen. nov., sp. nov. and Cedecea lapagei sp. nov., New Enterobacteriaceae from Clinical Specimens.
  • Kanakadandi2019 - A Rare Case of Cedecea Davisae Bacteremia Presenting as Biliary Sepsis.
  • Farmer2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Gammaproteobacteria Part B. Family Enterobacteriaceae, Genus IX. Cedecea
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CEDECEA DAVISAE
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR CEDECEA DAVISAE
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: April 08, 2021