Cellulomonas carbonis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Cellulomonas carbonis is a Gram-positive, non-spore-forming, aerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 74.4%. Cellulomonas carbonis is likely to be transient and not a long-term gut coloniser. (Shi2012)



  • This organism has been recovered from coal mine soil, China. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Aerobic and optimum growth temperature of 28C suggests this is an unlikely gut coloniser.
    • GENERAL CHARACTERISTICS (Shi2012);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; gelatin; starch;
  • 🧂
  • Salt tolerance:
  • tolerates 0% salt; tolerates 7% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0; tolerates pH 10; Grows optimally at pH 7.0.
  • 🌡
  • Temperature tolerance:
  • grows at 4℃; grows at 45℃; Grows optimally at 28℃.
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; fructose; galactose; glucose; mannose; xylose; cellubiose; lactose; maltose; melibiose; raffinose; sucrose; trehalose; D-turanose; sorbitol; N-Ac glucosamine;
  • ⥅
  • Substrates assimilated or utilised:
  • N-acetylglucosamine; L-arabinose; fructose; galactose; gluconate; glucose; glycogen; lactose; maltose; mannose; melibiose; raffinose; salicin; sorbitol; sucrose; xylose;
  • Active enzymes:
  • acid phosphatase; N-Ac β-glucosaminidase; catalase; esterase C4; α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; Leu arylamidase; naphthol-ASBI-P;
    • SPECIAL FEATURES (Shi2012);
    Character Response
  • ✓
  • Metabolites produced:
  • H₂S; ammonia;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Methyl red test:
  • not active
  • ✗
  • VP test:
  • not active
  • ✓
  • Nitrate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Shi2012);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; ampicillin; carbenicillin;
  • Cephalosporins:
  • cefepime; cefoxitin; cephalothin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • minocycline; tetracycline;
  • Quinolines:
  • norfloxacin; ofloxacin;
  • Aminoglycosides:
  • kanamycin; neomycin; streptomycin; tobramycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • chloramphenicol; nitrofurantoin;
  • Vancomycins:
  • vancomycin; teicoplanin;
  • Miscellaneous antibiotics:
  • lincomycin; novobiocin; polymyxin B;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinobacteria Order:  Micrococcales Family:  Cellulomonadaceae Genus:  Cellulomonas Gram stain:  + O2 Relation.:  aerobic Spore:  No spore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  coal mine soil, China
    DNA G+C(%):  74.4
    Opt. T:  28℃
    Low T(℃):  4(+)
    High T(℃):  45(+)
    NaCl 0.5-2%:  0(+)
    NaCl >6%:  7(+)
    Opt. pH:  7.0
    pH 6.0-8.0:  6.0(+)
    pH >8:  10(+)
    		Aesculin:  + Urea:  neg Gelatin:  + Starch:  + Casein:  neg DNA:  neg Tyrosine:  neg Tween:  80(neg)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  + Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Sorbose:  neg Xylose:  + Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  + Turanose:  + Inositol:  neg Mannitol:  neg Sorbitol:  + NAc-α-GA:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  + Fructose:  + Fucose:  neg Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Xylose:  + Lactose:  + Maltose:  + Melibiose:  + Raffinose:  + Sucrose:  + N_Acetyl_glucosamine:  + Gluconate:  + Glycogen:  + Inositol:  neg Mannitol:  neg Salicin:  + Sorbitol:  + Ala:  neg His:  neg Pro:  neg Ser:  neg Acetate:  neg Adipate:  neg Caprate:  neg Citrate:  neg 3-Hydroxybenzoate:  neg 4-Hydroxybenzoate:  neg Itaconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Lactate:  neg Malate:  neg Malonate:  neg Phenylacetate:  neg Propionate:  neg Suberate:  neg Valerate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg Ac-β-glcamnd:  + α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg Trypsin:  neg CystineAA:  neg LeuAA:  + ValAA:  neg AlkalineP:  neg AcidP:  + Esterase(C4):  + EstLip(C8):  neg Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  + Ammonia:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(30; disc)
    ampicillin:  S(10; disc)
    carbenicil:  S(100; disc)
    cefepime:  S(30; disc)
    cefoxitin:  S(30; disc)
    cephalothin:  S(30; disc)
    kanamycin:  S(30; disc)
    neomycin:  S(30; disc)
    streptomycin:  S(10; disc)
    tobramycin:  S(10; disc)
    erythromycin:  S(15; disc)
    norfloxacin:  S(10; disc)
    ofloxacin:  S(5; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    minocycline:  S(30; disc)
    tetracycline:  S(30; disc)
    teicoplanin:  S(30; disc)
    vancomycin:  S(30; disc)
    rifampicin:  S(5; disc)
    chloramphenicol:  S(30; disc)
    nitrofurantoin:  S(300; disc)
    lincomycin:  S(2; disc)
    novobiocin:  S(5; disc)
    polymyxin_B:  S(25; disc)

    References

    SPECIFIC REFERENCES FOR CELLULOMONAS CARBONIS
  • Shi2012 - Cellulomonas carbonis sp. nov., isolated from coal mine soil.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CELLULOMONAS CARBONIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
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    • Added: May 15, 2022