Cellulomonas timonensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Cellulomonas timonensis is a Gram-positive, Spore reported, facultatively anaerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 72.4%. Cellulomonas timonensis is probably a rare gut coloniser. (Ndongo2018a)



  • This organism has been recovered from the faeces of an obese patient (Ndongo2018a). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Ndongo2018a);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • 🧂
  • Salt tolerance:
  • tolerates 0% salt; tolerates 5% salt; Grows optimally with 1% salt.
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 7.
  • 🌡
  • Temperature tolerance:
  • grows at 28℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; fructose; galactose; glucose; mannose; ribose; xylose; aesculin; glycogen; starch; cellubiose; maltose; sucrose; trehalose; glycerol; arbutin; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • arabinose; glucose; mannose;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; N-Ac β-glucosaminidase; catalase; chymotrypsin; esterase C4; esterase lipase C8; β-galactosidase; β-glucosidase; Leu arylamidase; lipase C14; Val arylamidase; naphthol-ASBI-P;
    • SPECIAL FEATURES (Ndongo2018a);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
  • ✓
  • Nitrate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Ndongo2018a);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • oxacillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • fosfomycin; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin; teicoplanin;
  • Miscellaneous antibiotics:
  • clindamycin;
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Micrococcales Family:  Cellulomonadaceae Genus:  Cellulomonas Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  Spore reported Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  the faeces of an obese patient (Ndongo2018a)
    DNA G+C(%):  72.4
    Opt. T:  37℃
    Lower T(℃):  28(+)
    NaCl 0.5-2%:  0(+)
    NaCl 3-5%:  5(+)
    Opt. pH:  7
    		Aesculin:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  + Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + D-Lyxose:  neg Rhamnose:  neg Ribose:  + Sorbose:  neg D-Tagatose:  neg Xylose:  + L-Xylose:  neg Cellubiose:  + Gentiobiose:  neg Lactose:  neg Maltose:  + Melezitose:  neg Melibiose:  neg Sucrose:  + Trehalose:  + Turanose:  neg Amygdalin:  neg Aesculin:  + Glycogen:  + Inulin:  neg Starch:  + Adonitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  + Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  + Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  + Glucose:  + Mannose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Ac-β-glcamnd:  + α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  + α-Glucosidase:  neg β-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  neg Chymotrypsin:  + Trypsin:  neg CystineAA:  neg LeuAA:  + ValAA:  + AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    oxacillin:  Res
    penicillin:  Sens
    gentamicin:  Sens
    erythromycin:  Sens
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Sens
    teicoplanin:  Sens
    vancomycin:  Sens
    rifampicin:  Sens
    fosfomycin:  Res
    SXT:  Res
    clindamycin:  Sens
    colistin:  Res

    References

    SPECIFIC REFERENCES FOR CELLULOMONAS TIMONENSIS
  • Ndongo2018a - 'Cellulomonas timonensis' sp. nov., taxonogenomics description of a new bacterial species isolated from human gut.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CELLULOMONAS TIMONENSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: January 14, 2022