Chlamydia trachomatis

(aka Rickettsia trachomatis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Chlamydia trachomatis, (aka Rickettsia trachomatis), is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. Chlamydia trachomatis is unlikely to be a gut coloniser.



  • This organism has been recovered from clinical sources (sexually transmitted disease, arthritis). The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Is a known human pathogen. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • C. trachomatis is an obligate intracellular parasite that synthesises and accumulates glycogen. Survives outside the cell by producing infectious and resistant elementary bodies ('EB').
    • GENERAL CHARACTERISTICS
    Character Response
    SPECIAL FEATURES
    Character Response
    RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • amoxicillin;
  • Macrolides:
  • azithromycin; clarithromycin; erythromycin;
  • Tetracyclines:
  • doxycycline; tetracycline;
  • Quinolines:
  • levofloxacin; ofloxacin;
  • Aminoglycosides:
  • spectinomycin;
  • Heterocycles:
  • sulfadiazine;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Chlamydiae Class:  Chlamydiia Order:  Chlamydiales Family:  Chlamydiaceae Genus:  Chlamydia Alt. name:  Rickettsia trachomatis Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile
    Health:  Unknown
    Source:  clinical sources (sexually transmitted disease, arthritis)
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    spectinomycin:  S(≥0.8)
    azithromycin:  SensRNG: (0.016-0.125)
    erythromycin:  Sens
    clarithromycin:  S(0.03)
    levofloxacin:  Sens
    ofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Sens
    tetracycline:  Sens
    sulfadiazine:  Sens

    References

    SPECIFIC REFERENCES FOR CHLAMYDIA TRACHOMATIS
  • Everett1999 - Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CHLAMYDIA TRACHOMATIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022