Chryseobacterium hominis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Chryseobacterium hominis is a Gram-negative, non-spore-forming, aerobic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 36.5%. Chryseobacterium hominis is probably a rare gut coloniser. (Pfleiderer2013; Vaneechoutte2007; Bernardet2010Bergey)



  • This organism has been recovered from clinical sources (blood, wound - CCUG) and human faeces. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Could be a possible pathogen in humans, but unknown at this stage. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Pfleiderer2013); (Vaneechoutte2007); (Bernardet2010Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; DNA; starch;
  • ±
  • Strain-dependent hydrolysis or digestion:
  • tyrosine;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 3% salt;
  • 🌡
  • Temperature tolerance:
  • grows at 20℃; grows at 37℃; Grows optimally at 30℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; maltose;
  • ±
  • Strain-dependent acid from carbs:
  • sucrose;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; esterase lipase C8; γ-Glu transferase; α-glucosidase; Leu arylamidase; lipase; oxidase; pyrrolidine arylamidase; trypsin;
    • SPECIAL FEATURES (Vaneechoutte2007);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
  • ✗
  • ONPG test:
  • not active
  • ±
  • Nitrate:
  • reduced by most strains
  • ✓
  • Pigments:
  • produced
    • RESPONSE TO ANTIBIOTICS (Vaneechoutte2007);
    Class Active Resistant
  • Penicillins:
  • ampicillin;
  • Tetracyclines:
  • tetracycline;
  • Quinolines:
  • ciprofloxacin;
  • Heterocycles:
  • trimethoprim-sulfamethoxazole;

  • McLaughlin, S. D., Walker, A. W., Churcher, C., Clark, S. K., Tekkis, P. P., Johnson, M. W., Parkhill, J., Ciclitira, P. J., Dougan, G., Nicholls, R. J., & Petrovska, L. (2010). The bacteriology of pouchitis: a molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing. Annals of Surgery, 252(1), 90–98.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Flavobacteriia Order:  Flavobacteriales Family:  Weeksellaceae Genus:  Chryseobacterium Gram stain:  neg O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  +
    Health:  Unknown
    Source:  clinical sources (blood, wound - CCUG) and human faeces
    DNA G+C(%):  36.5
    Opt. T:  30℃
    Lower T(℃):  20(+)
    Mid T(℃):  37(+)
    NaCl 3-5%:  3(neg)
    		Aesculin:  + Urea:  neg Gelatin:  vr Starch:  + DNA:  d(+) Tyrosine:  d Tween:  80(neg)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Glucose:  + Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  + Sucrose:  d Trehalose:  neg Mannitol:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  + β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg γ-Glu transf.:  + LysDC:  neg OrnDC:  neg Trypsin:  + LeuAA:  + PyrrolidAA:  d(+) AlkalineP:  + AcidP:  + Esterase(C4):  vr EstLip(C8):  + Lipase:  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  + Pigment:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  R(10; disc)
    cefotaxime:  Var(MIC50): 30; disc), MIC90: Var(30; disc
    cephalothin:  Var(MIC50): 30; disc), MIC90: Var(30; disc
    gentamicin:  Var(MIC50): 10; disc), MIC90: Var(10; disc
    erythromycin:  Var(MIC50): 15; disc), MIC90: Var(15; disc
    ciprofloxacin:  S(5; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(30; disc)
    SXT:  S(25; disc)
    colistin:  Var(MIC50): 10; disc), MIC90: Var(10; disc

    References

    SPECIFIC REFERENCES FOR CHRYSEOBACTERIUM HOMINIS
  • Pfleiderer2013 - Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.
  • Vaneechoutte2007 - Chryseobacterium hominis sp. nov., to accommodate clinical isolates biochemically similar to CDC groups II-h and II-c.
  • Bernardet2010Bergey - Bergey's manual of systematic bacteriology. Vol. 4, The Fusobacteria. Family Flavobacteriaceae, Genus X. Chryseobacterium
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CHRYSEOBACTERIUM HOMINIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Pfleiderer2013 - Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • Added: April 08, 2021