Clostridium aminophilum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium aminophilum is a Gram-positive, spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. The DNA G+C content is 52.5%. Clostridium aminophilum is probably a rare gut coloniser.



  • This organism has been recovered from fistulated cattle. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • Asaccharolytic. Sodium is essential for growth
    • GENERAL CHARACTERISTICS
    Character Response
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 0% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 5.3;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 39℃; doesn't grow at 45℃;
  • ⥅
  • Substrates assimilated or utilised:
  • alanine; cysteine; glutamate; glycine; histidine; serine; threonine; glutamine; Casamino acids;
  • ±
  • Strain-dependent substrate utilisation:
  • pyroglutamate;
    • SPECIAL FEATURES
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; butyrate; lactate (trace); succinate (trace); H₂S; ammonia; indole;
  • ✗
  • Metabolites not produced:
  • H₂;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Lachnospiraceae Genus:  Clostridium Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  fistulated cattle
    DNA G+C(%):  52.5
    Lower T(℃):  25(+)
    Mid T(℃):  39(+)
    High T(℃):  45(neg)
    NaCl 0.5-2%:  0(neg)
    pH 4.2-5.9:  5.3(+)
    		Aesculin:  neg Gelatin:  neg Casein:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Ala:  + Arg:  neg Asp:  neg Cys:  + Glu:  + Gly:  + His:  + Ile:  neg Leu:  neg Lys:  neg Phe:  neg Pro:  neg Ser:  + Thr:  + Trp:  neg Tyr:  w Val:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Butyrate:  + Lactate:  trace(+) Succinate:  trace(+) H2S:  + Ammonia:  + H2:  neg Indole:  +

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM AMINOPHILUM
  • Chua2018 - Intestinal Dysbiosis Featuring Abundance of Ruminococcus gnavus Associates With Allergic Diseases in Infants
  • DeAngelis2013 - Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified
  • Paster1993 - Phylogeny of the ammonia-producing ruminal bacteria Peptostreptococcus anaerobius, Clostridium sticklandii, and Clostridium aminophilum sp. nov.
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    • Added: September 19, 2022