Clostridium carboxidivorans

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium carboxidivorans is a Gram-positive, rarely spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 31-32%. Clostridium carboxidivorans is probably a rare gut coloniser. (Rainey2011aBergey; Liou2005)



  • This organism has been recovered from settling lagoon. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • Consumes H2/CO2 or CO autotrophically. Cellulolytic. Homoacetogen.
    • GENERAL CHARACTERISTICS (Rainey2011aBergey); (Liou2005);
    Character Response
  • Substrates hydrolysed or digested:
  • cellulose;
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 6.2.
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 38℃.
  • ⥅
  • Substrates assimilated or utilised:
  • L-arabinose; cellubiose; cellulose; ethanol; fructose; galactose; glucose; glycerol; inositol; mannitol; mannose; melezitose; pectin; propanol; rhamnose; ribose; starch; sucrose; trehalose; xylose; alanine; aspartate; betaine; glutamate; histidine; serine; citrate; butanol; glutamine; L-asparagine; Casamino acids;
    • SPECIAL FEATURES (Rainey2011aBergey); (Liou2005);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; butyrate; ethanol; butanol;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Rare Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  settling lagoon
    DNA G+C(%):  31-32
    Opt. T:  38℃
    Opt. pH:  6.2
    		Aesculin:  neg Urea:  neg Gelatin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg L-Arabinose:  + Fructose:  + Fucose:  neg Galactose:  + Glucose:  + Mannose:  + Rhamnose:  + Ribose:  + Xylose:  + Cellubiose:  + Lactose:  neg Maltose:  neg Melezitose:  + Melibiose:  neg Raffinose:  neg Sucrose:  + Trehalose:  + Amygdalin:  neg Cellulose:  + Ethanol:  + Gluconate:  neg Glycerol:  + Inositol:  + Mannitol:  + Methanol:  neg Pectin:  + Propanol:  + Sorbitol:  neg Starch:  + Ala:  + Arg:  neg Asp:  + Betaine:  + Glu:  + His:  + Ser:  + Citrate:  + Lactate:  neg Malate:  neg Succinate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Butyrate:  + Ethanol:  + Butanol:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM CARBOXIDIVORANS
  • Rainey2011aBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Clostridiaceae, Genus I. Clostridium - Cluster I
  • Liou2005 - Clostridium carboxidivorans sp. nov., a solvent-producing clostridium isolated from an agricultural settling lagoon, and reclassification of the acetogen Clostridium scatologenes strain SL1 as Clostridium drakei sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM CARBOXIDIVORANS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Qin2012 - Metagenome-wide association study of gut microbiota in type 2 diabetes
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    • Added: January 14, 2022