Clostridium celatum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium celatum is a Gram-positive, spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 8 gut microbiome compilation studies or metastudies. Clostridium celatum is probably a common, although minor, coloniser of the gut. (Rainey2011aBergey)



  • This organism has been recovered from human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal. Robust growth can have positive consequences for gut health.
    • GENERAL CHARACTERISTICS (Rainey2011aBergey);
    Character Response
  • ±
  • Strain-dependent hydrolysis or digestion:
  • milk;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 6.5% salt;
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 20% bile
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; doesn't grow at 45℃; Grows optimally at 37℃.
  • Active enzymes:
  • urease;
    • SPECIAL FEATURES (Rainey2011aBergey);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; butyrate (minor); ethanolminor; succinate (trace); Hâ‚‚S (variable); Hâ‚‚;
  • Haemolysis:
  • alpha (variable)
  • Nitrate:
  • reduction is variable

  • Hauschild, A. H. W., & Holdeman, L. V. (1974). Clostridium celatum sp.nov., Isolated from Normal Human Feces. International Journal of Systematic Bacteriology, 24(4), 478–481.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod
    Health:   Positive
    Source:  human faeces
    Opt. T:  37℃
    Lower T(℃):  30(+)
    High T(℃):  45(neg)
    NaCl >6%:  6.5(neg)
    Bile reaction(%):  20(neg)
    		Milk:  curdle(w)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Gluconate:  neg Thr:  neg Lactate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  + Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  + Acetate:  + Butyrate:  minor(+) Ethanol:  minor Succinate:  trace(+) H2S:  vr H2:  +

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM CELATUM
  • Rainey2011aBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Clostridiaceae, Genus I. Clostridium - Cluster I
  • Gao2020 - Functional Microbiomics Reveals Alterations of the Gut Microbiome and Host Co-Metabolism in Patients With Alcoholic Hepatitis
  • Huang2019 - Analysis of microbiota in elderly patients with Acute Cerebral Infarction
  • KowalskaDuplaga2019 - Differences in the intestinal microbiome of healthy children and patients with newly diagnosed Crohn's disease
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM CELATUM
  • Benno1986 - Comparison of the fecal microflora in rural Japanese and urban Canadians.
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Chen2020 - Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR CLOSTRIDIUM CELATUM
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021