Clostridium cellulosi

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium cellulosi is a Gram-negative, spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 35%. Clostridium cellulosi is likely to be transient and not a long-term gut coloniser. (He1991)



  • This organism has been recovered from human faeces and cow manure. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Cellulolytic. High optimum growth temperature so unlikely to be a gut coloniser.
    • GENERAL CHARACTERISTICS (He1991);
    Character Response
  • Substrates hydrolysed or digested:
  • cellulose;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.2; tolerates pH 8.5; Grows optimally at pH 7.3-7.5.
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 30℃; grows at 40℃; grows at 65℃; Grows optimally at 55-60℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; xylose; cellulose; aesculin; glycogen; inulin; starch; cellubiose; lactose; melibiose; raffinose; sucrose; trehalose; inositol; mannitol; salicin;
    • SPECIAL FEATURES (He1991);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; ethanol; CO₂; H₂;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • VP test:
  • active
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  human faeces and cow manure
    DNA G+C(%):  35
    Opt. T:  55-60℃
    Lower T(℃):  30(neg)
    Mid T(℃):  40(+)
    High T(℃):  65(+)
    Opt. pH:  7.3-7.5
    pH 6.0-8.0:  6.2(+)
    pH >8:  8.5(+)
    		Gelatin:  neg Meat:  c
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Sorbose:  neg Xylose:  + Cellubiose:  + Lactose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  + Cellulose:  + Aesculin:  + Glycogen:  + Inulin:  + Starch:  + Erythritol:  neg Glycerol:  neg Inositol:  + Mannitol:  + Sorbitol:  neg Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Ethanol:  + CO2:  + H2:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM CELLULOSI
  • He1991 - Two cellulolytic Clostridium species: Clostridium cellulosi sp. nov. and Clostridium cellulofermentans sp. nov.
  • Nylund2013 - Microarray analysis reveals marked intestinal microbiota aberrancy in infants having eczema compared to healthy children in at-risk for atopic disease
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM CELLULOSI
  • Salonen2014 - Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men.
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    • Added: January 04, 2022