Clostridium cellulovorans

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium cellulovorans is a Gram-negative, spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 26-27%. Clostridium cellulovorans is probably a rare gut coloniser. (Sleat1984)



  • This organism has been recovered from batch methanogenic fermentation. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal. Robust growth can have positive consequences for gut health.
    • QUIRKS
  • Can't utilise starch or proteolyse protein.
    • GENERAL CHARACTERISTICS (Sleat1984);
    Character Response
  • Substrates hydrolysed or digested:
  • pectin;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.4-7.8; Grows optimally at pH 7.
  • 🌡
  • Temperature tolerance:
  • grows at 20℃; grows at 40℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; sorbose; cellulose; pectin; xylan; cellubiose; lactose;
    • SPECIAL FEATURES (Sleat1984);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; butyrate; lactate; COâ‚‚; Hâ‚‚;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod
    Health:   Positive
    Source:  batch methanogenic fermentation
    DNA G+C(%):  26-27
    Opt. T:  37℃
    Lower T(℃):  20(+)
    Mid T(℃):  40(+)
    Opt. pH:  7
    pH 6.0-8.0:  6.4-7.8(+)
    		Pectin:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Fructose:  + Galactose:  + Glucose:  + Mannose:  + Sorbose:  + Cellubiose:  + Lactose:  + Cellulose:  + Starch:  neg Pectin:  + Xylan:  +

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM CELLULOVORANS
  • Sleat1984 - Isolation and Characterization of an Anaerobic, Cellulolytic Bacterium, Clostridium cellulovorans sp. nov.
  • Malham2019 - The microbiome reflects diagnosis and predicts disease severity in paediatric onset inflammatory bowel disease
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM CELLULOVORANS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • New2022 - Collective effects of human genomic variation on microbiome function.
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    • Added: March 18, 2022