Clostridium colicanis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium colicanis is a Gram-negative, spore-forming, anaerobic, non-motile, rod-shaped bacterium. The DNA G+C content is 37.1%. Clostridium colicanis is probably a rare gut coloniser. (Greetham2003)



  • This organism has been recovered from canine faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Greetham2003);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; urea;
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 45℃; Grows optimally at 37-40℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; ribose; cellubiose; lactose; maltose; sucrose;
  • Active enzymes:
  • alkaline phosphatase; Arg arylamidase; arginine dihydrolase; N-Ac β-glucosaminidase; β-galactosidase; Gly arylamidase; His arylamidase; Leu arylamidase; Leu-Gly arylamidase;
    • SPECIAL FEATURES (Greetham2003);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Haemolysis:
  • absent
  • ✓
  • NO3➔NO2:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Goldstein2014);
    Class Active Resistant
  • Macrolides:
  • fidaxomicin;
  • Heterocycles:
  • metronidazole;
  • NOTES

    Clostridia

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  neg O2 Relation.:  anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  canine faeces
    DNA G+C(%):  37.1
    Opt. T:  37-40℃
    Lower T(℃):  30(+)
    High T(℃):  45(+)
    		Aesculin:  + Urea:  + Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  + Xylose:  neg Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  neg Sucrose:  + Trehalose:  neg Amygdalin:  neg Aesculin:  w Glycogen:  neg Starch:  w Inositol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  w
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg G6PDH6PGDH:  neg α-Arab:  neg Ac-β-glcamnd:  + α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  + α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg ArgDH:  + GluDC:  neg AlanineAA:  neg ArgAA:  + GluGluAA:  neg GlyAA:  + HisAA:  + LeuAA:  + LeuGlyAA:  + ProAA:  neg PheAA:  neg PyrogluAA:  neg SerAA:  neg TyrAA:  neg AlkalineP:  + Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    fidaxomicin:  S(0.03)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  RNG: (2-32)
    metronidazole:  S(2)

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM COLICANIS
  • Greetham2003 - Clostridium colicanis sp. nov., from canine faeces.
  • Goldstein2014 - Comparative in vitro activities of SMT19969, a new antimicrobial agent, against 162 strains from 35 less frequently recovered intestinal Clostridium species: implications for Clostridium difficile recurrence.
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    • Added: October 08, 2022