Clostridium colinum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium colinum is a Gram-positive, spore-forming, anaerobic, motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 43%. Clostridium colinum is probably a rare gut coloniser. (Rainey2011hBergey; Berkhoff1985)



  • This organism has been recovered from birds, and is an avian pathogen. Has been detected in human faeces. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: animal pathogen). Could be a possible pathogen in humans, but unknown at this stage. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Rainey2011hBergey); (Berkhoff1985);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • ±
  • Strain-dependent hydrolysis or digestion:
  • starch;
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 35-42℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; mannose; raffinose; sucrose; trehalose;
  • ±
  • Strain-dependent acid from carbs:
  • mannitol;
    • SPECIAL FEATURES (Rainey2011hBergey); (Berkhoff1985);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • NO3➔NO2:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  + O2 Relation.:  anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  birds, and is an avian pathogen. Has been detected in human faeces
    DNA G+C(%):  43
    Opt. T:  35-42℃
    		Aesculin:  + Urea:  neg Gelatin:  neg Starch:  d(neg) Casein:  neg Milk:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  w Glucose:  + Mannose:  + Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  w Melezitose:  neg Melibiose:  neg Sucrose:  + Trehalose:  + Glycogen:  neg Erythritol:  neg Inositol:  neg Mannitol:  d Sorbitol:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Lactate:  neg Pyruvate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  + Acetate:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM COLINUM
  • Rainey2011hBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Clostridiaceae, Genus I. Clostridium - Cluster XIVb
  • Berkhoff1985 - Clostridium colinum sp. nov., nom. rev., the Causative Agent of Ulcerative Enteritis (Quail Disease) in Quail, Chickens, and Pheasants
  • Bajer2017 - Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM COLINUM
  • PerezBrocal2015 - Metagenomic Analysis of Crohn's Disease Patients Identifies Changes in the Virome and Microbiome Related to Disease Status and Therapy, and Detects Potential Interactions and Biomarkers
  • Salonen2014 - Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men.
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    • Added: October 28, 2021