Clostridium culturomicium

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium culturomicium is a Gram-positive, spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. The DNA G+C content is 32.2%. Clostridium culturomicium is probably a rare gut coloniser. (Kieu2021)



  • This organism has been recovered from human faeces (obese). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Kieu2021);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 7.5% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 7.0; tolerates pH 8.5;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • D-tagatose; aesculin; 5-ketogluconate;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; N-Ac β-glucosaminidase; esterase C4; esterase lipase C8; β-galactosidase; β-glucuronidase; naphthol-ASBI-P;
    • RESPONSE TO ANTIBIOTICS (Kieu2021);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; benzylpenicillin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (obese)
    DNA G+C(%):  32.2
    Opt. T:  37℃
    Lower T(℃):  25(+)
    High T(℃):  45(+)
    NaCl >6%:  7.5(+)
    pH 6.0-8.0:  7.0(+)
    pH >8:  8.5(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Tagatose:  + Aesculin:  + 5-Ketogluconate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Ac-β-glcamnd:  + β-Galactosidase:  + β-Glucuronidase:  + AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    benzyl-pen:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Sens
    metronidazole:  Sens

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM CULTUROMICIUM
  • Kieu2021 - Clostridium culturomicium sp. nov. and Clostridium jeddahitimonense sp. nov., novel members of the Clostridium genus isolated from the stool of an obese Saudi Arabian.
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    • Added: April 08, 2023