Clostridium drakei

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium drakei is a Gram-positive, spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 30-32%. Clostridium drakei is likely to be transient and not a long-term gut coloniser. (Liou2005)



  • This organism has been recovered from an acidic coal-mine pond, Germany. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Can grow autotrophically with H2/CO2 or CO. Homoacetogen.
    • GENERAL CHARACTERISTICS (Liou2005);
    Character Response
  • pH
  • Acidity tolerance:
  • tolerates pH 4.6; tolerates pH 7.8; Grows optimally at pH 5.4-7.0.
  • 🌡
  • Temperature tolerance:
  • grows at 18℃; grows at 42℃; Grows optimally at 30-37℃.
  • ⥅
  • Substrates assimilated or utilised:
  • L-arabinose; cellubiose; cellulose; ethanol; fructose; fucose; galactose; gluconate; glucose; glycerol; inositol; mannitol; mannose; melezitose; propanol; rhamnose; ribose; starch; sucrose; xylose; alanine; arginine; aspartate; betaine; glutamate; histidine; serine; citrate; fumarate; lactate; malate; butanol; glutamine; L-asparagine; Casamino acids; H2 consumed; CO2 consumed;
    • SPECIAL FEATURES (Liou2005);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; ethanol; butanol;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • Methyl red test:
  • active
  • ✗
  • VP test:
  • not active
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  an acidic coal-mine pond, Germany
    DNA G+C(%):  30-32
    Opt. T:  30-37℃
    Low T(℃):  18(+)
    High T(℃):  42(+)
    Opt. pH:  5.4-7.0
    pH 4.2-5.9:  4.6(+)
    pH 6.0-8.0:  7.8(+)
    		Gelatin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg L-Arabinose:  + Fructose:  + Fucose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  + Ribose:  + Xylose:  + Cellubiose:  + Lactose:  neg Maltose:  neg Melezitose:  + Melibiose:  neg Raffinose:  neg Sucrose:  + Trehalose:  neg Amygdalin:  neg Cellulose:  + Ethanol:  + Gluconate:  + Glycerol:  + Inositol:  + Mannitol:  + Methanol:  neg Pectin:  neg Propanol:  + Sorbitol:  neg Starch:  + Ala:  + Arg:  + Asp:  + Betaine:  + Glu:  + His:  + Ser:  + Citrate:  + Fumarate:  + Lactate:  + Malate:  + Succinate:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Ethanol:  + Butanol:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM DRAKEI
  • Liou2005 - Clostridium carboxidivorans sp. nov., a solvent-producing clostridium isolated from an agricultural settling lagoon, and reclassification of the acetogen Clostridium scatologenes strain SL1 as Clostridium drakei sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM DRAKEI
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: March 18, 2022